Actively Recruiting

Phase 3
FEMALE
Healthy Volunteers
NCT06919614

STI Testing to Enhance PrEP Use in Pregnancy

Led by Botswana Harvard AIDS Institute Partnership · Updated on 2025-07-29

600

Participants Needed

1

Research Sites

219 weeks

Total Duration

On this page

Sponsors

B

Botswana Harvard AIDS Institute Partnership

Lead Sponsor

U

University of Washington

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women start and continue using PrEP during and after pregnancy. Pregnant women (n=600) seeking antenatal care in Botswana will be enrolled and randomly assigned to receive the standard of care (standard STI assessment with no STI testing) versus STI testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis during pregnancy and postpartum. The investigators' hypothesis is that providing STI testing alongside PrEP offer will encourage more women to start and continue using PrEP.

CONDITIONS

Official Title

STI Testing to Enhance PrEP Use in Pregnancy

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant and seeking antenatal care
  • Self-identify as a cis-gender woman
  • Living without HIV
  • Not currently using PrEP
  • Plan to remain in the city or town of enrolment until 9 months post-delivery
  • Plan to receive antenatal and postnatal care in the city or town of enrolment
  • Willing and able to provide informed consent
Not Eligible

You will not qualify if you...

  • Male gender
  • Not pregnant
  • Living with HIV
  • Currently using PrEP
  • Not planning to remain in the city or town of enrolment until 9 months post-delivery
  • Not planning to receive antenatal and postnatal care in the city or town of enrolment
  • Not able or willing to provide informed consent for participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

DHMT Clinics

Gaborone, Botswana

Actively Recruiting

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Research Team

C

Chelsea Morroni, MBChB, DFSRH, MPH, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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STI Testing to Enhance PrEP Use in Pregnancy | DecenTrialz