Actively Recruiting
Stimulant Effects on Disruptive Behavior
Led by Matthew J O'Brien, PhD, BCBA-D · Updated on 2025-03-17
10
Participants Needed
1
Research Sites
460 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an effective evaluation of the impact of stimulant medication on these behaviors. Three behavior assessments for children and adolescents diagnosed with AD/HD who exhibit disruptive behavior will be conducted: 1. Preference assessments will be conducted to determine whether preference for social and nonsocial items and activities differs under medication and non-medication conditions. 2. Functional analyses will be conducted to determine whether stimulant medication has an effect on the frequency and function or purpose of disruptive behavior. 3. Choice assessments will be conducted to evaluate the impact of stimulant medication on impulse control/delay discounting. This study will be conducted in three phases. For each of the 5 to 10 participants there will be 8 total visits. The first 4 visits will entail a preference assessment, followed by a functional analysis. On visits 1 and 3, the participant will be asked to take his/her stimulant medication as is typically done; however, on visits 2 and 4, the participant will be asked to refrain from taking the medication. For visits 5-8, participants will continue to participate in preference assessments, but will also be presented with a choice arrangement with work and play. In the choice arrangement, participants will be given four work cards and four play cards that they can organize in any order. Work cards will be associated with a brief academic task and play cards will be associated with a brief play period using high-preferred toys/activities. On visits 5 and 7 the participant will be asked to take his or her stimulant medication as usual, while on visits 6 and 8 the participant will be asked to refrain from taking his or her medication.
CONDITIONS
Official Title
Stimulant Effects on Disruptive Behavior
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Child or adolescent aged between 4 years 0 months and 12 years 11 months
- Valid diagnosis of attention deficit/hyperactivity disorder (AD/HD)
- Exhibits disruptive behavior, including physical or verbal aggression, self-injury, destruction of property, noncompliance, tantrums, or diagnosis of disruptive behavior disorder or oppositional defiant disorder
- Currently prescribed a stimulant medication at an age-appropriate dose
You will not qualify if you...
- Diagnosis of autism, conduct disorder, or moderate to profound intellectual disability
- Taking a stimulant dosage outside the recommended therapeutic range
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
Actively Recruiting
Research Team
M
Matthew J O'Brien, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here