Actively Recruiting
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Led by Jorge Gonzalez-Martinez · Updated on 2025-11-10
60
Participants Needed
1
Research Sites
419 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study the investigators aim to enroll patients scheduled to undergo deep brain stimulation (DBS) implantation for movement disorders for intra-operative testing. In addition to standard-of-care surgical procedure to implant deep brain stimulation electrode leads, participants will also be stimulated and recorded from cortical areas by a temporary strip electrode (1X6) in the subdural space. The electrodes will be connected to external stimulators and a series of experiments will be performed to assess effects of the DBS on movement quality and electrophysiology measures. Results of this study will elucidate the biological mechanisms related to deep brain stimulation in modulating motor and speech function in patients with abnormal movement disorders.
CONDITIONS
Official Title
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with essential tremor scheduled for deep brain stimulation surgery at UPMC Presbyterian with asymmetric symptoms, testing the least affected arm
- Patients with Parkinson's Disease scheduled for deep brain stimulation surgery at UPMC Presbyterian
- Confirmation that insurance coverage for the standard procedure will not be affected by study participation
You will not qualify if you...
- History of seizures
- Significant bilateral tremor preventing completion of motor tasks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
C
Cierra Clark, MS
CONTACT
E
Elvira Pirondini, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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