Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06078176

Stimulation for Bowel Emptying

Led by VA Office of Research and Development · Updated on 2026-04-13

12

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

Sponsors

V

VA Office of Research and Development

Lead Sponsor

C

Cleveland Functional Electrical Stimulation Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which means that stools take longer than normal to pass through the colon. This slowed movement may result in chronic constipation and difficulty emptying the bowels. Individuals typically (without or without caregiver assistance) insert a gloved finger into the rectum and gently stretch it to improve colonic motility for a brief period to empty the bowels. The investigators hypothesize that electrically stimulating the rectum, instead of mechanically stretching it, will produce the same beneficial effect of improving colonic motility. Therefore, this study will compare the two methods. If electrical stimulation effectively improves colonic motility, then the investigator shall develop the approach as a therapeutic intervention in future studies.

CONDITIONS

Official Title

Stimulation for Bowel Emptying

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suprasacral spinal cord injury
  • Diagnosed neurogenic bowel dysfunction and using digital rectal stimulation
  • Bowel routine requires at least 30 minutes or at least 3 cycles of digital rectal stimulation
  • Neurologically stable
  • At least 18 years old
  • At least 12 months post neurological injury or disease diagnosis
Not Eligible

You will not qualify if you...

  • Active sepsis
  • Open pressure sores on or around pelvis
  • Significant colon trauma or colostomy
  • Crohn's disease
  • Colonic obstruction or gastrointestinal surgery within last 3 months
  • Significant history of autonomic dysreflexia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Syracuse VA Medical Center, Syracuse, NY

Syracuse, New York, United States, 13210-2716

Actively Recruiting

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Research Team

C

Cesar Colasante-Garrido, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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