Actively Recruiting
Stimulation of External Carotid Artery Circulation
Led by The University of Texas Medical Branch, Galveston · Updated on 2026-02-20
12
Participants Needed
1
Research Sites
80 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is testing a new approach to help people with migraine headaches. Researchers want to find out if using electrical stimulation to affect blood flow in the external carotid artery is safe and practical for helping control headaches. The goal of the study is to determine whether this approach could improve headache symptoms and overall outcomes for people with migraines.
CONDITIONS
Official Title
Stimulation of External Carotid Artery Circulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years
- Chronic migraine, status migrainosus, or craniofacial pain not responding to maximum medical therapy
- Undergoing middle meningeal artery intra-arterial lidocaine infusion
- Provided informed consent
You will not qualify if you...
- Allergy to lidocaine
- Seizure disorder, history of seizures, or increased seizure risk
- Intracranial vascular malformations or dural arteriovenous fistula
- Hemodynamic instability or conditions posing risk with brief blood flow changes
- Previous middle meningeal artery intervention or craniotomy causing artery occlusion
- Any implanted electronic device (pacemaker, ICD, DBS, VNS, cochlear implant, spinal cord stimulator)
- Significant cardiovascular disease (unstable angina, severe arrhythmias, recent myocardial infarction)
- Severe autonomic dysfunction
- Active systemic infection
- Vulnerable populations including pregnant individuals, children, prisoners, those lacking decision-making capacity, persons with cognitive impairment, or unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Medical Branch
Galveston, Texas, United States, 77555-0133
Actively Recruiting
Research Team
M
Matias Costa, MD
CONTACT
P
Patrick Karas, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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