Actively Recruiting
Stimulation-Induced Changes in Fronto-Limbic Network
Led by University of Alabama at Birmingham · Updated on 2026-05-13
30
Participants Needed
1
Research Sites
212 weeks
Total Duration
On this page
Sponsors
U
University of Alabama at Birmingham
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation. This study will use standard behavioral emotion processing tasks combined with neural recording and direct brain stimulation to assess different aspects of emotion processing. Stimulation pulses during pre and post-test periods will assess the effects of stimulation before and after conditioning, the results of which will be combined with results from the activity of each electrode during the emotion tasks to inform us of the nature of emotion processing in the brain and allow us to devise brain modulation protocols in the future.
CONDITIONS
Official Title
Stimulation-Induced Changes in Fronto-Limbic Network
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Implantation of sEEG electrodes for standard of care epilepsy surgery evaluation
- Cognitive ability to perform simple tasks and understand instructions
- Implanted electrodes located in the amygdala and medial prefrontal cortex regions
- Ability to understand and sign written informed consent
You will not qualify if you...
- Inability to complete the task
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Epilepsy Monitoring Unit UAB Hospital
Birmingham, Alabama, United States, 35233
Actively Recruiting
Research Team
R
Rebekah Chatfield, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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