Actively Recruiting
Stimulation of the Larynx to Treat Unexplained Chronic Cough
Led by University of Minnesota · Updated on 2025-08-11
60
Participants Needed
1
Research Sites
337 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.
CONDITIONS
Official Title
Stimulation of the Larynx to Treat Unexplained Chronic Cough
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-88
- Cough lasting longer than 8 weeks
- Cough visual analogue scale (VAS) rating of 30 or greater on a 0-100 scale
- Ability to provide informed consent and complete questionnaires independently
- Ability to read and speak English
You will not qualify if you...
- Presence of electronic implants such as pacemakers
- Current speech therapy for cough
- Contraindications to safe or effective use of the vibrotactile stimulation device
- No regular access to wifi internet
- Neuromuscular impairments affecting cough or laryngeal sensation/function (e.g., multiple system atrophy, Parkinson's disease, stroke, vocal fold paralysis or paresis)
- Untreated carotid disease
- Body mass index (BMI) over 40
- Current smoking or quit smoking less than 3 months ago
- Known infectious causes of cough (e.g., tuberculosis, pertussis, COVID-19)
- History of known or suspected aspiration pneumonia
- Diagnosis or suspicion of chronic obstructive pulmonary disease (COPD)
- Diagnosis or suspicion of interstitial lung disease (ILD)
- Unmanaged acid reflux
- Unmanaged allergies or postnasal drip
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
C
Clinical Research Coordinators Ashley Ramaker, MS or colleagues
CONTACT
A
Ali Stockness
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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