Actively Recruiting

All Genders
ID06982235

Stone and Laser Therapies Post-Market Study evaluating Boston Scientific devices in urinary tract procedures and BPH treatment

Led by Boston Scientific Corporation · Updated on 2026-05-12

238

Participants Needed

5

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

The SALT study focuses on collecting ongoing safety and performance information about Boston Scientific's medical devices used in urinary tract diagnostic and therapeutic procedures, including treatments for benign prostatic hyperplasia (BPH). This multi-center, open-label observational study monitors these devices after they are already available on the market to better understand their real-world use and effects. Participants include adults undergoing procedures involving these devices for urinary tract issues or BPH with related symptoms. The study involves two groups: one undergoing urinary tract procedures with the study devices, and the other receiving BPH treatment using the devices. The devices being evaluated include the LithoVue Elite Single-Use Digital Flexible Ureteroscope System with intrarenal pressure monitoring and the Pulse 120H Holmium Laser System with MOSES 2.0 Technology. These devices are used during the diagnostic or therapeutic procedures or surgical treatment as applicable. Participants will be followed for one year after their procedure to track safety events and device performance. Researchers will monitor serious adverse events related to the devices from the procedure through 12 months afterward. They will also assess stone clearance rates 21 to 90 days post-procedure and changes in BPH symptoms at six months. Participants will attend follow-up visits to report outcomes and ensure ongoing monitoring of safety and device effectiveness in everyday use.

CONDITIONS

Brief Title

Stone and Laser Therapies Post-Market Study (SALT)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • For urinary tract procedure cohort: Subject plans to undergo diagnostic and/or therapeutic urinary tract procedure with Boston Scientific device(s)
  • Subject is willing and able to complete all follow-up visits
  • For BPH cohort: Subject is 40 years of age or older
  • Subject has a diagnosis of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms
  • Subject plans to undergo BPH treatment with Boston Scientific device(s)
  • Subject is willing and able to complete all follow-up visits
Not Eligible

You will not qualify if you...

  • For urinary tract procedure cohort: Subject requires simultaneous surgical treatment for BPH
  • Subject is unwilling or unable to provide consent
  • Any condition that prevents study participation, such as history of medical non-compliance
  • For BPH cohort: Subject requires simultaneous upper urinary calculi lithotripsy procedure (except bladder calculi)
  • Subject is unwilling or unable to provide consent
  • Any condition that prevents study participation, such as history of medical non-compliance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Day of the procedure

Participants undergo diagnostic and/or therapeutic urinary tract procedures or BPH treatment using Boston Scientific study devices.

1 procedure visit (in-person)

Long-term Monitoring

Duration - Up to 12 months

Participants are followed for safety and device performance for up to 12 months after the procedure.

Regular follow-up visits over 12 months

Trial Site Locations

Total: 5 locations

1

Mayo Clinic Phoenix

Phoenix, Arizona, United States, 85054

Actively Recruiting

2

University of Miami Hospital

Miami, Florida, United States, 33442

Actively Recruiting

3

University of South Florida

Tampa, Florida, United States, 33606

Actively Recruiting

4

Indiana University Medical Center

Indianapolis, Indiana, United States, 46202

Actively Recruiting

5

Duke University Medical Center

Durham, North Carolina, United States, 27710

Actively Recruiting

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Research Team

W

Winnie Chen

C

Curtis Blackwell

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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