Actively Recruiting

All Genders
NCT06572046

STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies

Led by IRCCS Fondazione Stella Maris · Updated on 2026-03-27

500

Participants Needed

1

Research Sites

309 weeks

Total Duration

On this page

Sponsors

I

IRCCS Fondazione Stella Maris

Lead Sponsor

I

IRCCS Eugenio Medea

Collaborating Sponsor

AI-Summary

What this Trial Is About

Our goal is to create a solid and harmonious disease registry of patient affected by hereditary spastic paraplegia (HSP) that facilitates the collection and management of patients' data over time encouraging the research and the development of future clinical trials. In-depth clinical phenotyping will develop significant clinical outcome measures that can be used in clinical trials and will allow the phenotypic complexity of the disease to be captured with the use of validated clinical scales, biomarkers and so-called patient reported outcomes (PROs).

CONDITIONS

Official Title

STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of pure or complex hereditary spastic paraplegia (HSP) or spastic ataxia, even without a known genetic diagnosis
  • Participants or their parents/legal guardians must provide informed consent for enrollment and data privacy management
Not Eligible

You will not qualify if you...

  • Presence of secondary forms of hereditary spastic paraplegia
  • Comorbidities that significantly affect the overall clinical condition as judged by the doctor
  • Lack of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Fondazione Stella Maris

Pisa, Italy, 56128

Actively Recruiting

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Research Team

F

Filippo M Santorelli, Dr.

CONTACT

S

Sara Satolli, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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