Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06808776

Stories to Prevent (StoP) HPV Cancers

Led by Milton S. Hershey Medical Center · Updated on 2026-02-24

200

Participants Needed

1

Research Sites

71 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial (RCT) evaluates the association of a narrative communication intervention on human papillomavirus (HPV) vaccination rates among 9- to 12-year-olds. The intervention is a brief video from local cancer survivors narrating their stories with an HPV-related cancer diagnosis and recommending the HPV vaccine for cancer prevention. RCT participants will be the parents (n=200) of children ages 9-12 who have not initiated HPV vaccination. Participants will be randomized (1:1) to our intervention or control (placebo video) one week before their child's next primary care visit. Our primary outcome is HPV vaccine initiation (first dose of the HPV vaccine series) among children ages 9-12 at the time of the wellness visit. The study also explores the effect of narratives on theory-based mediators of HPV vaccination, including parents' cognitive (e.g., risk perception) and emotional reactions (e.g., hope, anticipated regret).

CONDITIONS

Official Title

Stories to Prevent (StoP) HPV Cancers

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Parent or guardian of a 9-12 year old receiving primary care at a Penn State Health clinic
  • Child has not previously received or started the HPV vaccine
  • Able to read and understand spoken English or Spanish
  • Has a valid email address and access to a mobile phone, tablet, desktop, or laptop computer
Not Eligible

You will not qualify if you...

  • Parent or guardian is younger than 18 years old
  • Unable to read and understand spoken English or Spanish
  • Does not have access to a mobile phone, tablet, desktop, or laptop computer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Penn State Health

Hershey, Pennsylvania, United States, 17033

Actively Recruiting

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Research Team

W

William A Calo, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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