Actively Recruiting
Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)
Led by University of Aarhus · Updated on 2025-12-15
216
Participants Needed
5
Research Sites
183 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective is to investigate if abrupt withdrawal versus gradual withdrawal of pharmacotherapy (solifenacin and/or mirabegron) influences the risk of recurrence of incontinence. Children aged 5-14 years diagnosed with urinary incontinence, treated with pharmacotherapy of solifenacin and/or mirabegron and ready for withdrawal will be randomized 1:1 to either abrupt or gradual withdrawal, according to the medical treatment that the child is receiving.
CONDITIONS
Official Title
Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- The participant's custody holder(s) must voluntarily sign and date an informed consent before starting any study procedures.
- Child aged 5 to 14 years at the time of consent and inclusion.
- Diagnosed with urinary incontinence according to ICCS criteria.
- Currently treated with solifenacin and/or mirabegron.
- Continence achieved while on solifenacin and/or mirabegron therapy.
- Previous withdrawal attempts are allowed.
- Continence maintained on the same medication dose for at least three months.
You will not qualify if you...
- Inability of the participant or parental custody holder to understand written and spoken Danish.
- Presence of neurogenic detrusor overactivity (neurogenic bladder).
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Department of Pediatric and Adolescent Medicine, Aalborg University Hospital
Aalborg, Aalborg, Denmark, 9000
Actively Recruiting
2
Department of Pediatric and Adolescent Medicine, Aarhus University Hospital
Aarhus, Aarhus N, Denmark, 8200
Actively Recruiting
3
Department of Pediatric and Adolescent medicine, Esbjerg Hospital
Esbjerg, Esbjerg, Denmark, 6700
Not Yet Recruiting
4
Department of Pediatric and Adolescent Medicine, Gødstrup Hospital
Herning, Herning, Denmark, 7400
Actively Recruiting
5
Department of Pediatric and Adolescent Medicine, Kolding Hospital
Kolding, Kolding, Denmark, 6000
Not Yet Recruiting
Research Team
A
Ann-Kristine Mandøe Svendsen, MD
CONTACT
L
Luise Borch, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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