Actively Recruiting
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
Led by Linkoeping University · Updated on 2025-01-22
90
Participants Needed
2
Research Sites
481 weeks
Total Duration
On this page
Sponsors
L
Linkoeping University
Lead Sponsor
R
Region Östergötland
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms (hot flushes) in postmenopausal women. The main question it aims to answer is the effect of 15 weeks of strength training vs high intensity aerobic training vs unchanged physical activity on frequency and severity of hot flushes. Participants will be randomised to: 1. strength training 2. high-intensity aerobic training 3. untreated control group. Researchers will compare strength training, high-intensity aerobic training and untreated control group to see if training can reduce hot flushes.
CONDITIONS
Official Title
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Postmenopausal women defined by one of the following: 12 months or more since last menstruation; amenorrhea due to intrauterine device or hysterectomy with Follicle Stimulating Hormone (FSH) >30 mIU/ml; bilateral oophorectomy; or induced menopause due to chemotherapy or radiation with at least 2 years of amenorrhea
- At least 28 moderate to severe hot flushes per week during a 2-week screening period recorded in a daily diary
- Age 45 years or older
- Physical ability to participate in strength training or high-intensity aerobic exercise for 60 minutes, three times per week, for 15 weeks
- Ability to understand Swedish orally and in writing
You will not qualify if you...
- Regular physical activity exceeding 30 minutes per week of vigorous intensity or 150 minutes of moderate intensity or combined activities totaling more than 150 minutes of moderate intensity
- Use of systemic menopausal hormone therapy in the last 2 months
- Use of natural or herbal preparations or other medications for hot flushes in the last 2 months
- Capillary hemoglobin level below 110 g/l
- Blood pressure higher than 160 mmHg systolic or 100 mmHg diastolic
- Unstable medical conditions that could affect hot flushes, such as unregulated thyroid disease
- Any medical condition judged by a physician as inappropriate for participation due to potential effects on hot flushes or risk of injury with vigorous exercise
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Region Kalmar Län
Kalmar, Sweden, S-39126
Actively Recruiting
2
Region Östergötland
Linköping, Sweden, S-58185
Actively Recruiting
Research Team
A
Anna-Clara Spetz Holm, Ass prof, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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