Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
Healthy Volunteers
NCT07104539

Strength Training Response of Muscle in GLP-1 Users

Led by Virginia Polytechnic Institute and State University · Updated on 2026-01-21

30

Participants Needed

1

Research Sites

81 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.

CONDITIONS

Official Title

Strength Training Response of Muscle in GLP-1 Users

Who Can Participate

Age: 50Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 years or older
  • Currently taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less
  • Weight less than 300 pounds
  • Passed a health and exercise readiness screening
Not Eligible

You will not qualify if you...

  • Age under 50 years
  • Weight more than 300 pounds
  • Diagnosis of osteoporosis
  • Active metabolic, neoplastic, or cardiovascular disease
  • Unable or unwilling to provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Virginia Tech

Blacksburg, Virginia, United States, 24061

Actively Recruiting

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Research Team

K

Kevin Davy

CONTACT

E

Elaina Marinik

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Strength Training Response of Muscle in GLP-1 Users | DecenTrialz