Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
Healthy Volunteers
NCT07122960

Strengthening Informed Consent for Authentic Participation in Perinatal HIV Research

Led by Columbia University · Updated on 2025-08-14

60

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

E

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study evaluates a visual Informed Consent Form (ICF) compared to a standard, text-only ICF as an approach to achieving meaningful consent into a clinical trial. The visual ICF uses cartoon characters, graphics and easy-to-understand text to cover the full content of a standard, text-only ICF. In this study, women who are considering enrollment into a clinical trial of a nutrition intervention for their infants will be randomized to either the visual ICF or to the text-only ICF. Qualitative and quantitative data will be collected immediately after the consent process and 8 weeks later. In addition, women not eligible for enrollment into the infant nutrition trial will be asked questions about their opinions regarding the visual ICF. The overall goal of the sub-study is to inform efforts to improve meaningful consent into clinical trials by evaluating whether the visual ICF improves understanding of the trial.

CONDITIONS

Official Title

Strengthening Informed Consent for Authentic Participation in Perinatal HIV Research

Who Can Participate

Age: 18Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women ages 18-45 years
  • Pregnant women or women who have given birth within the past 2 to 6 weeks
Not Eligible

You will not qualify if you...

  • Unwilling to provide consent
  • Severe maternal or infant illness such as tuberculosis or major psychiatric or neurological conditions
  • Inability to communicate in English, isiXhosa, or Afrikaans

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stellenbosch University Wooster Rural Campus

Worcester, Western Cape, South Africa, 6850

Actively Recruiting

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Research Team

L

Louise Kuhn, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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