Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06471751

Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-01-29

38

Participants Needed

2

Research Sites

82 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Saint Etienne

Lead Sponsor

A

Association aide à la recherche médicale de proximité (AIRE)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Obstructive Sleep Apnea hypopnea Syndrome (OSAS), whose prevalence is 4% of the French population, can lead to serious health consequences (risk of road accidents, onset of cardiovascular disease, etc.). OSAS corresponds to a certain number of interruptions (apneas) or reductions (hypopneas) of ventilation during sleep. The weakening of the tone of the inspiratory and oropharyngeal muscles is one of the main causes of upper airways obstruction during the inspiratory phase.

CONDITIONS

Official Title

Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Moderate SAHOS (15 3 AHI 3 30)
  • Body Mass Index (BMI) < 35
  • Patient affiliated or entitled to a social security scheme
  • Patient having signed a consent to participate in the study
Not Eligible

You will not qualify if you...

  • Excessive daytime sleepiness: Epworth sleepiness score > 10
  • Professional driving and history of accidents related to sleepiness
  • Severe obstructive or restrictive ventilatory disorders of neuromuscular origin authenticated by respiratory function tests
  • Patients undergoing treatment for OSAS or requiring immediate initiation of continuous positive airway pressure (CPAP) or a mandibular advancement orthosis
  • Patients who have stopped CPAP or orthosis treatment in less than one month
  • Patients undergoing cardiorespiratory exercise rehabilitation or starting regular physical training
  • Uncompensated heart failure, thoracic sternotomy surgery < 4 months
  • Marked osteoporosis with history of rib fractures
  • History of spontaneous pneumothorax
  • Severe asthma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

CHU de Grenoble

Grenoble, France, 38000

Not Yet Recruiting

2

Centre Hospitalier Universitaire

Saint-Etienne, France, 42055

Actively Recruiting

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Research Team

A

Amandine ZELLAG, physiotherapist

CONTACT

P

Pierre LABEIX, physiotherapist

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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