Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
NCT05795179

Stress & Self-Control Costs

Led by NYU Langone Health · Updated on 2026-03-11

300

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

Sponsors

N

NYU Langone Health

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms underlying these costs are unknown. To address this, the investigators will use a validated decision-making task that measures how much individuals will pay (from a study endowment) to restrict access to tempting rewards that may lead to self-control failures. The investigators will examine these costs to identify their cognitive, neural and affective mechanisms. First, the investigators will identify the cognitive and computational mechanism that gives rise to self-control costs. Second, the investigators will characterize the neural correlates of self-control costs and identify neural mediators and connectivity patterns stemming from these costs. Finally, the investigators will examine how different classes of stressors (physical, social, or lifetime stress) shape the behavioral and neural representations of self-control costs.

CONDITIONS

Official Title

Stress & Self-Control Costs

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18-70 years of age, able to speak, read, and write fluently in English
  • Willing and able to follow study procedures and provide informed consent
  • Currently on a diet to maintain or lose weight and implementing or maintaining dietary changes
Not Eligible

You will not qualify if you...

  • History of or medication for neurologic or psychiatric disease
  • High blood pressure or heart condition
  • Diabetes, food allergies, metabolic disorders, or history of eating disorder
  • Use of corticosteroids or beta-blockers
  • Metallic implants or devices contraindicating magnetic resonance imaging
  • Pregnancy due to stress and scanning procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

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Research Team

C

Candace Raio

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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Stress & Self-Control Costs | DecenTrialz