Actively Recruiting
Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).
Led by Loma Linda University · Updated on 2026-01-30
98
Participants Needed
1
Research Sites
170 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare difference between Aspirin 81 mg and Aspirin 325 mg in preventing strokes in patients with head and neck vessels injury. The main questions it aims to answer are: * If Aspirin 81 mg efficacy in prevention of stroke in patients with head and neck vessels injury is not lower than and Aspirin 325 mg. * If rate of hemorrhagic complications in patients with head and neck vessels injury taking Aspirin 81 mg is not higher than patients that take Aspirin 325 mg.
CONDITIONS
Official Title
Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosis of blunt cerebrovascular injury by computed tomography angiography (CTA) upon admission
You will not qualify if you...
- Age under 18 years
- Pregnant women
- No access to take Aspirin by mouth or feeding tube
- Current treatment with Heparin drip or other full-dose anticoagulation at BCVI diagnosis
- Use of anti-platelet medications other than Aspirin at BCVI diagnosis
- Patients with BCVI grade 5 injury based on Biffl classification
- Any contraindication or history of allergy to Aspirin
- Acute stroke matching the injured vessel territory at BCVI diagnosis
- Acute spinal trauma requiring surgical intervention
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Loma Linda University Medical Center
Loma Linda, California, United States, 92354
Actively Recruiting
Research Team
M
Maryam B Tabrizi, M.D
CONTACT
S
Sina Asaadi, M.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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