Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
All Genders
ID04498598

Structural Modification In Supraglottic Airway Device Enhances Exchange Between Supraglottic & Endotracheal Ventilation Modes

Led by The Cleveland Clinic · Updated on 2026-05-07

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a new modification to the supraglottic airway (SGA) device designed to improve airway management during general anesthesia. This modified device, called the A/Z modification, features an opening that allows an endotracheal tube (ETT) to be inserted through the SGA body without needing an exchange catheter. This innovation aims to enable easy conversion between supraglottic and endotracheal ventilation modes during surgery, addressing complications related to airway management, ventilation therapy, hypoxia, and hypoventilation. The study involves patients undergoing general anesthesia who require airway management for ventilation. Participants will receive the A/Z modified supraglottic airway device, which can be converted reversibly to endotracheal ventilation by replacing a special adapter piece with an ETT. This device modification has been professionally manufactured and tested for feasibility on manikins before clinical trial use. The intervention focuses on how well the device supports oxygenation and ventilation and how successfully it allows switching between ventilation modes during and immediately after use. During the study, participants will receive airway management with the A/Z modified device while under general anesthesia for surgical procedures. Researchers will measure the rate of successful oxygenation and ventilation, as well as the ease of converting between supraglottic and endotracheal ventilation. These outcomes will be assessed during and immediately after the intervention. The trial excludes patients with anticipated airway difficulties or other factors that could affect airway management. Participation lasts through the anesthesia procedure and immediate recovery period to evaluate device performance and safety.

CONDITIONS

Brief Title

Structural Modification In Supraglottic Airway Device

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients
  • Scheduled for a general anesthesia procedure with endotracheal tube and muscle relaxation
Not Eligible

You will not qualify if you...

  • Patients unable to consent
  • Non English speaking
  • History of difficult airway
  • Physical exam suggesting difficult airway or need for special equipment
  • Body mass index greater than 35
  • Gastroesophageal reflux disease
  • Anesthetic plan other than general anesthesia
  • Emergency procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - During the surgical procedure

Participants undergo airway management using the A/Z modified supraglottic airway device during general anesthesia for their surgical procedure.

1 surgical procedure visit (in-person)

Trial Site Locations

Total: 1 location

1

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

R

Rafi Avitsian, MD

M

Mark Mettler

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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