Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06027671

Structured Peer-delivered ART and Reentry Community Strategy

Led by Johns Hopkins University · Updated on 2026-02-11

400

Participants Needed

1

Research Sites

193 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

A

Aurum Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The overarching goal of this study is to implement a transition community adherence club strategy (Full-SPARCS) for HIV-positive individuals transitioning from correctional to community settings in South Africa. The investigators seek to provide actionable findings to inform policy decisions to contribute to HIV care continuity with this population. The investigators note that effectiveness and scalability often conflict with intervention design; thus, the investigators have proposed testing whether a group approach is effective and the investigators will assess the costs of each component * To compare the effectiveness of Full-SPARCS to care as usual to achieve HIV RNA suppression 6 months following correctional facility release * To assess determinants of implementation of Full-SPARCS * To assess the scalability through costing and cost effectiveness analysis of Full-SPARCS

CONDITIONS

Official Title

Structured Peer-delivered ART and Reentry Community Strategy

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Incarcerated at one of the participating study enrolment sites, including both un-sentenced and sentenced individuals
  • Diagnosed with HIV and receiving antiretroviral therapy (ART) at the time of enrolment
  • Expected release or trial date within three months of study enrolment
  • Plan to reside in an unrestricted environment within Ekurhuleni, Tshwane, or Johannesburg districts of Gauteng Province
  • Residence must be within approximately 20 km, 45-minute travel time, or two local taxi minibus rides to a SPARCS intervention site
  • Willing to participate in follow-up activities after release and provide contact information
Not Eligible

You will not qualify if you...

  • Younger than 18 years old
  • Severe cognitive dysfunction or mental illness preventing informed consent
  • Unable to provide informed consent to participate
  • Assessed by Department of Correctional Services health staff as needing high-intensity care beyond study support
  • Not released from the correctional facility during the intervention period
  • Release planned to a region outside of Gauteng Province

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

The Aurum Institute - Head office

Johannesburg, Gauteng, South Africa, 2193

Actively Recruiting

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Research Team

C

Christopher Hoffmann

CONTACT

T

Tonderai Mabuto

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

2

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