Actively Recruiting
Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-03-06
100
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective is to study the phenotypic, functional and metabolomic characteristics of neutrophils circulating subpopulations in lung cancer patients, and to compare them to a control group of healthy volunteers. A blood sample will be taken before the first treatment session for the lung cancer patient and a second blood sample will be taken during the first evaluation visit. The investigators hypothesize that there may be different circulating neutrophil subpopulations in patients with metastatic non-small cell lung cancer (NSCLC) involved in tumor progression and resistance to immunotherapy.
CONDITIONS
Official Title
Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Male or female
- Affiliated with a Health Insurance
- Diagnosis of metastatic stage lung cancer with mutation status, treatment-nafve
You will not qualify if you...
- Tuberculosis or other acute or chronic bacterial infections
- Chronic progressive viral infections (Hepatitis B and C, HIV)
- Previous or ongoing chemotherapy
- Unable to provide informed consent
- Opposition to the research
- Participation in another research study with an exclusion period still in progress at pre-inclusion
- Vulnerable individuals such as pregnant, parturient, or breastfeeding women; persons under guardianship or curatorship; or deprived of liberty by judicial or administrative decision
- Patients benefiting from the AME
AI-Screening
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Trial Site Locations
Total: 1 location
1
Assistance Publique - Hôpitaux de Paris (AP-HP) - Cochin Hospital - Pneumology unit
Paris, Île-de-France Region, France, 75014
Actively Recruiting
Research Team
M
Marie WISLEZ, Pr
CONTACT
M
Marie BENHAMMANI-GODARD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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