Actively Recruiting
Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell
Led by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Updated on 2025-07-23
6
Participants Needed
1
Research Sites
387 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being done to determine if the investigational radiotracer called 111In-XYIMSR-01 is helpful in detecting clear cell renal cell carcinoma tissue in your body when used during a SPECT-CT Scan
CONDITIONS
Official Title
Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female sex
- 18 years of age or older
- Willing to provide signed informed consent and follow the study requirements
- Histological confirmation of renal cell carcinoma with a clear cell component
- 2 to 10 sites of disease measuring at least 1.5 cm on contrast-enhanced CT or MRI scan of chest, abdomen, and pelvis done within 60 days before enrollment
- Screening lab values within specified limits: serum bilirubin 1.5 times upper limit of normal (up to 3 times for Gilbert's syndrome), ALT 3 times upper limit, AST 3 times upper limit, creatinine clearance 50 mL/min, absolute neutrophil count 1,500/mm3, platelets 100,000/mm3, hemoglobin 9.0 g/dL, white blood cell count 2,000/mm3
You will not qualify if you...
- Received systemic therapy for clear cell renal cell carcinoma within 12 months before enrollment
- Received any radioisotope within five physical half-lives before study drug injection
- Any medical condition or circumstance that could interfere with reliable data or study completion as judged by the investigator
- Women of child-bearing potential without a negative pregnancy test within 24 hours before imaging
- Women who are breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Johns Hopkins University
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
Y
Yasser Ged, MBBS
CONTACT
J
Jasmine Brooks
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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