Actively Recruiting
Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-03-10
140
Participants Needed
7
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, investigators will compare standard Aerobic Training/AT with adaptive Aerobic Training/AT. Standard AT will be a fixed (unchanging) amount of walking each week, while adaptive AT will adjust the level of exercise depending on participants' response to the exercise. Investigators will see how both study approaches (standard AT and adaptive AT) affect participants' CRF.
CONDITIONS
Official Title
Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Female
- Diagnosed with primary breast cancer confirmed by histology or standard imaging
- Scheduled to receive neoadjuvant or adjuvant chemotherapy
- Performing at least 90 minutes of moderate or strenuous exercise weekly by self-report
- Willing to follow all study procedures
- Able to achieve acceptable baseline cardiopulmonary exercise test results based on oxygen consumption plateau, respiratory exchange ratio ≥ 1.10, peak heart rate within 10 bpm of predicted maximum, or high perceived exertion
You will not qualify if you...
- Enrolled in other interventional investigational studies unless approved by the principal investigator
- Receiving treatment for any other invasive cancer
- Having distant metastatic cancer
- Mental impairment interfering with cooperation
- Contraindications to cardiopulmonary exercise testing, including recent heart attack, unstable angina, uncontrolled arrhythmia, recurrent fainting, active infection of the heart, myocarditis or pericarditis, severe aortic stenosis, uncontrolled heart failure, recent pulmonary embolism, lower limb thrombosis, suspected aneurysm, uncontrolled asthma, pulmonary edema, respiratory failure, acute non-cardiopulmonary disorders affecting exercise, or low blood oxygen at rest (≤85%)
- Any other condition deemed by the investigator to make participation unsafe or unsuitable
AI-Screening
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Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Limited protocol activities)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Limited protocol activities)
Rockville Centre, New York, United States, 11553
Actively Recruiting
Research Team
J
Jessica Scott, PhD
CONTACT
A
Anthony Yu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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