Actively Recruiting
A Study of AMC6156 in People With Sarcopenia
Led by Animuscure Inc. · Updated on 2025-07-29
80
Participants Needed
4
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial aims to find out whether AMC6156 can improve physical function and is safe in older adults with sarcopenia. Participants will take AMC6156 or a placebo daily for 12 weeks, and their movement, strength, and safety will be regularly monitored through tests and checkups.
CONDITIONS
Official Title
A Study of AMC6156 in People With Sarcopenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary participation with written informed consent
- Male aged 65 years or older or postmenopausal female
- Diagnosed with sarcopenia: ASM less than 7.0 kg/m² (men) or less than 5.4 kg/m² (women)
- Low handgrip strength or Short Physical Performance Battery (SPPB) score 9 or less
- Mini Nutritional Assessment (MNA) screening score 8 or higher
- Body weight 35 kg or more, BMI between 15 and 30 kg/m²
- Willing and able to follow exercise and nutrition guidance
You will not qualify if you...
- Allergy to the investigational drug
- History of gastrointestinal bleeding, ulcers, or severe liver, kidney, or heart disease
- QTc interval 450 ms or greater with symptoms
- Severe chronic obstructive pulmonary disease (COPD), uncontrolled diabetes, or thyroid disease
- Diseases causing cachexia or muscle wasting such as ALS or Parkinson's disease
- Vitamin D deficiency below 10 ng/mL or hemoglobin less than 10 g/dL
- Severe psychiatric disorders or Mini-Mental State Examination (MMSE) score less than 21
- Inability to walk or recent fracture/surgery affecting mobility
- Use of prohibited medications or recent participation in other clinical trials
- Investigator considers the participant unsuitable for the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
CHA Bundang Medical Center
Seongnam-si, Gyeonggi-do, South Korea, 13496
Actively Recruiting
2
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 13620
Not Yet Recruiting
3
Ajou University Hospital
Suwon, Gyeonggi-do, South Korea, 16499
Actively Recruiting
4
Seoul National University Hospital
Seoul, Seoul, South Korea, 03080
Actively Recruiting
Research Team
J
Jooyeon Kim
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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