Actively Recruiting
Study of Antitumor Immune Response After cCRT and IO Treatment in Non-resectable III Stage NSCLC Patients
Led by Fundación GECP · Updated on 2026-01-28
50
Participants Needed
22
Research Sites
161 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Observational, multicenter, one-arm, non-comparative study. Data will be recorded in a retrospectively manner. The study will be based on secondary data collected from patient clinical chart completed by the doctor during routine visits. The primary objective is describe the antitumor immune response generated in the context of IO (immunotherapy) treatment after cCRT in patients with unresectable NSCLC treated in real world.
CONDITIONS
Official Title
Study of Antitumor Immune Response After cCRT and IO Treatment in Non-resectable III Stage NSCLC Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with histologically- or cytologically-documented NSCLC presenting unresectable stage IIIA, IIIB, or IIIC disease as per the 8th edition lung cancer staging manual
- ECOG performance status of 0 or 1
- PD-L1 expression greater than 1%
- Age 18 years or older at time of study
- Patients without progression after concurrent chemo-radiotherapy who will receive Durvalumab immunotherapy for 12 months following standard practice
- Ability to comply with treatment and attend follow-up visits
- Signed, dated, and IRB/EC-approved informed consent form
You will not qualify if you...
- Refusal to sign and date an IRB/IEC-approved informed consent form
- Inability to undergo venipuncture
- Any medical, mental, or psychological condition that would prevent completion of the study or understanding of study information as per investigator's opinion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 22 locations
1
Complejo Hospitalario Universitario Del Ferrol
Ferrol, A Coruña, Spain, 15405
Actively Recruiting
2
Hospital General Universitario de Alicante
Alicante, Alicante, Spain, 03010
Actively Recruiting
3
ICO Badalona, Hospital Germans Trias i Pujol
Badalona, Barcelona, Spain, 08916
Actively Recruiting
4
Hospital Universitari Vall d' Hebron
Barcelona, Barcelona, Spain, 08035
Actively Recruiting
5
Hospital de la Santa Creu i Sant Pau
Barcelona, Barcelona, Spain, 08041
Actively Recruiting
6
Hospital De Basurto
Bilbao, Bilbao, Spain, 48013
Actively Recruiting
7
Hospital General Universitario de Ciudad Real
Ciudad Real, Ciudad Real, Spain, 13005
Actively Recruiting
8
ICO Girona, Hospital Josep Trueta
Girona, Girona, Spain, 17007
Actively Recruiting
9
Hospitalario Universitario A Coruña
A Coruña, La Coruña, Spain, 15006
Actively Recruiting
10
Hospital Universitari de Gran Canària Doctor Negrín
Las Palmas de Gran Canaria, Las Palmas, Spain, 35010
Actively Recruiting
11
Hospital Universitario Lucus Augusti
Lugo, Lugo, Spain, 27003
Actively Recruiting
12
Hospital Universitario De La Princesa
Madrid, Madrid, Spain, 28006
Actively Recruiting
13
Hospital Clínico San Carlos
Madrid, Madrid, Spain, 28040
Actively Recruiting
14
Hospital Universitario Fundación Jiménez Díaz
Madrid, Madrid, Spain, 28040
Actively Recruiting
15
Hospital Universitario La Paz
Madrid, Madrid, Spain, 28046
Actively Recruiting
16
Hospital Universitario Puerta de Hierro
Majadahonda, Madrid, Spain, 28222
Actively Recruiting
17
Hospital Universitario Central De Asturias
Oviedo, Oviedo, Spain, 33011
Actively Recruiting
18
Hospital Universitario Nuestra Señora de Candelaria
Santa Cruz de Tenerife, Santa Cruz de Tenerife, Spain, 38010
Actively Recruiting
19
Hospital Virgen del Rocio
Seville, Sevilla, Spain, 41013
Actively Recruiting
20
Hospital Universitario Y Politécnico La Fe
Valencia, Valencia, Spain, 46026
Actively Recruiting
21
Hospital Clínico Universitario de Valladolid
Valladolid, Valladolid, Spain, 47003
Actively Recruiting
22
Complexo Hospitalario Universitario De Vigo
Vigo, Vigo, Spain, 36204
Actively Recruiting
Research Team
E
Eva Pereira
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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