Actively Recruiting
A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis
Led by Amgen · Updated on 2025-12-01
48
Participants Needed
7
Research Sites
677 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this study is to evaluate the long-term safety of apremilast in subjects 2 years of age or older with oral ulcers associated with Behçets disease or 5 years of age or older with active juvenile psoriatic arthritis that have completed Study 20190530 or Study 20190529.
CONDITIONS
Official Title
A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Informed consent or assent obtained
- Completed 52 weeks of treatment in the core study
- Under 18 years old at time of consent
- Age- and sex-specific BMI at or above the 5th percentile per CDC growth charts
- Willing to follow study visit schedule and protocol
- Considered to have acceptable benefit/risk for continued apremilast treatment
You will not qualify if you...
- Positive response to any question on the Columbia-Suicide Severity Rating Scale at Week 52 of the core study
- Scheduled surgery or other interventions that would disrupt study participation
- Female participants of childbearing potential unwilling to use required contraception during treatment and 30 days after last dose
- Female participants planning pregnancy during the study or within 30 days after last dose
- Female participants with a positive pregnancy test at Week 0
- Known sensitivity to any study products administered during dosing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
General Hospital of Thessaloniki Ippokrateio
Thessaloniki, Greece, 54642
Actively Recruiting
2
Meir Medical Center
Kfar Saba, Israel, 4428164
Actively Recruiting
3
Hospital Universitari i Politecnic La Fe
Valencia, Valencia, Spain, 46026
Actively Recruiting
4
Hospital Universitario Ramon y Cajal
Madrid, Spain, 28034
Actively Recruiting
5
Hacettepe Universitesi Tip Fakultesi Hastanesi
Ankara, Turkey (Türkiye), 06100
Actively Recruiting
6
Istanbul Universitesi Cerrahpasa Tip Fakultesi
Istanbul, Turkey (Türkiye), 34098
Actively Recruiting
7
Umraniye Egitim ve Arastirma Hastanesi
Istanbul, Turkey (Türkiye), 34764
Actively Recruiting
Research Team
A
Amgen Call Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here