Actively Recruiting

Age: 15Years - 75Years
All Genders
Healthy Volunteers
NCT07392411

Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

Led by Beijing Tiantan Hospital · Updated on 2026-02-06

720

Participants Needed

1

Research Sites

179 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research employs AI to analyze facial expressions and speech patterns, aiming to develop new digital tools for diagnosing and differentiating Parkinson's disease and similar disorders.

CONDITIONS

Official Title

Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

Who Can Participate

Age: 15Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Parkinson's disease according to 2015 Movement Disorder Society criteria
  • Age between 18 and 75 years old
  • Early-stage Parkinson's with Hoehn-Yahr score ≤ 2.5 or mid-to-late-stage with score between 2.5 and 5
  • Willingness to undergo facial expression video and speech audio recording
  • Signed informed consent form
  • For Parkinson's plus syndromes group: diagnosis of Multiple System Atrophy or Progressive Supranuclear Palsy per Chinese diagnostic criteria
  • Age between 18 and 75 years old
  • Willingness to undergo facial expression video and speech audio recording
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • History of cerebrovascular disease, head trauma, hydrocephalus, brain tumors, or intracranial surgery
  • Presence of metal implants, cardiac pacemakers, or other metallic foreign bodies (for Parkinson's disease patients)
  • Severe dyskinesia in Parkinson's disease patients interfering with video/audio recording cooperation
  • Mini-Mental State Examination (MMSE) score ≤ 24 points

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

首都医科大学附属北京天坛医院

Beijing, Beijing Municipality, China, 100070

Actively Recruiting

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Research Team

L

Lingyan Ma, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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