Actively Recruiting

Age: 18Years +
All Genders
NCT05317494

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Greece

Led by AbbVie · Updated on 2025-07-16

100

Participants Needed

13

Research Sites

235 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Acute Myeloid Leukemia (AML) is a cancer of the blood and bone marrow and is the most common acute leukemia in adults. This study will evaluate how well Venetoclax works to treat AML in adult participants who are ineligible for intensive chemotherapy in Greece. Venetoclax is a drug approved to treat Acute Myeloid Leukemia. All study participants will receive Venetoclax as prescribed by their study doctor in accordance with approved local label. Adult participants with a new diagnosis of AML who are ineligible for intensive chemotherapy will be enrolled. Around 100 participants will be enrolled in the study in approximately 15 sites in Greece. Participants will receive venetoclax tablets to be taken by mouth daily according to the approved local label. The duration of the study is approximately 30 months. There is expected to be no additional burden for participants in this trial. All study visits will occur during routine clinical practice and participants will be followed for 30 months.

CONDITIONS

Official Title

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Greece

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Acute Myeloid Leukemia (AML) and ineligible for intensive chemotherapy
  • Eligible to receive Venetoclax as a first-line therapy according to Greek Ministry of Health label
  • Physician has decided to start Venetoclax treatment before enrolling in the study
Not Eligible

You will not qualify if you...

  • Participating in an interventional clinical trial within 30 days before starting Venetoclax treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

Olympion General Clinic /ID# 268392

Pátrai, Achaia, Greece, 25443

Active, Not Recruiting

2

General Hospital of Athens Gennimatas /ID# 245968

Athens, Attica, Greece, 11527

Active, Not Recruiting

3

General Hospital of Athens Laiko /ID# 244338

Athens, Attica, Greece, 11527

Active, Not Recruiting

4

University General Hospital Attikon /ID# 248265

Athens, Attica, Greece, 12462

Active, Not Recruiting

5

University General Hospital of Heraklion PA.G.N.I /ID# 244337

Heraklion, Crete, Greece, 71500

Completed

6

General University Hospital of Alexandroupolis /ID# 244235

Alexandroupoli, Greece, 68100

Active, Not Recruiting

7

General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 244339

Athens, Greece, 10676

Active, Not Recruiting

8

General Anti-cancer Hospital Agios Savvas /ID# 244408

Athens, Greece, 11522

Active, Not Recruiting

9

General Hospital of Athens Laiko - Hematology Location /ID# 244234

Athens, Greece, 11527

Active, Not Recruiting

10

University General Hospital of Ioannina /ID# 244336

Ioannina, Greece, 45500

Active, Not Recruiting

11

University General Hospital of Patras /ID# 244335

RION Patras Achaia, Greece, 26504

Completed

12

Papageorgiou General Hospital /ID# 248266

Thessaloniki, Greece, 56429

Actively Recruiting

13

General Hospital of Thessaloniki George Papanikolaou /ID# 244237

Thessaloniki, Greece, 57010

Active, Not Recruiting

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Research Team

A

ABBVIE CALL CENTER

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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