Actively Recruiting

Age: 18Years +
All Genders
NCT07284342

A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa

Led by AbbVie · Updated on 2026-04-13

103

Participants Needed

14

Research Sites

58 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Parkinson's disease (PD) is a neurological condition, which affects the brain. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess change in sleep disturbances of adult participants with advanced Parkinson's disease receiving subcutaneous Foslevodopa/Foscarbidopa under routine clinical practice. Foslevodopa/Foscarbidopa is an approved drug for the treatment of Parkinson's Disease. Approximately 103 adult participants who are prescribed Foslevodopa/Foscarbidopa by their doctors will be enrolled across approximately 20 sites across Spain. Participants will receive Foslevodopa/Foscarbidopa subcutaneous infusion as prescribed by their physician. Participants will be followed for up to 12 weekss. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

CONDITIONS

Official Title

A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older with advanced Parkinson's disease diagnosed as levodopa-responsive idiopathic PD
  • Prescribed Foslevodopa/Foscarbidopa subcutaneous infusion in routine clinical practice following approved product guidelines
  • Mini-Mental State Examination score of 24 or higher to ensure ability to follow study procedures
  • Decision to treat with Foslevodopa/Foscarbidopa subcutaneous infusion made by clinician before study enrollment
  • Participants with moderate to severe obstructive sleep apnea may participate if they use CPAP at least 4 hours/night for 70% of nights in the last month or use a mandibular advancement device and have an Apnea-Hypopnea Index below 15
Not Eligible

You will not qualify if you...

  • Participants with contraindications to Foslevodopa/Foscarbidopa subcutaneous infusion as per approved product guidelines
  • Participants currently enrolled in interventional research studies (excluding non-interventional studies, post-marketing observational studies, or registries) at enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 14 locations

1

Hospital Regional Universitario de Malaga /ID# 276357

Málaga, Andalusia, Spain, 29010

Actively Recruiting

2

Hospital Universitari Son Espases /ID# 276349

Palma, Balearic Islands, Spain, 07120

Actively Recruiting

3

Hospital Universitario Marques de Valdecilla /ID# 276315

Santander, Cantabria, Spain, 39008

Actively Recruiting

4

Hospital General Universitario Santa Lucía /ID# 277222

Cartagena, Murcia, Spain, 30202

Actively Recruiting

5

Hospital de Cabuenes /ID# 276314

Gijón, Principality of Asturias, Spain, 33394

Actively Recruiting

6

Hospital Universitario Virgen del Rocio /ID# 277806

Seville, Sevilla, Spain, 41013

Actively Recruiting

7

Hospital Universitario Torrecárdenas /ID# 276899

Almería, Spain, 04009

Actively Recruiting

8

Hospital Universitario Vall de Hebron /ID# 276318

Barcelona, Spain, 08035

Actively Recruiting

9

Hospital Santa Creu i Sant Pau /ID# 276319

Barcelona, Spain, 08041

Actively Recruiting

10

Hospital Universitario De Burgos /ID# 276317

Burgos, Spain, 09006

Actively Recruiting

11

Hospital Universitario Virgen de las Nieves /ID# 276350

Granada, Spain, 18014

Actively Recruiting

12

Hospital Universitario Clinico San Cecilio /ID# 276356

Granada, Spain, 18016

Actively Recruiting

13

Complejo Hospitalario Universitario de Pontevedra /ID# 276313

Pontevedra, Spain, 36071

Actively Recruiting

14

Hospital Universitario De Toledo /ID# 276884

Toledo, Spain, 45007

Actively Recruiting

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Research Team

A

AbbVie Spain

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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