Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT06312085

A Study to Assess the Clinical Success of Root Canal Treatment Using Novel Obturation Material.

Led by Lumendo AG · Updated on 2024-07-12

63

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

Sponsors

L

Lumendo AG

Lead Sponsor

A

Avania

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is prospective, single-arm, non-randomized controlled trial to test the effectiveness, safety and performance of a novel dental obturation material. The main question sit answers is 1. To test the effectiveness of the Endofill device for root canal obturation up to 12-month follow-up period. 2. To test the performance of the Endofill device evaluated with periapical radiographs immediately on completion of procedure. The participants requiring root canal treatment will be treated with obturated using Endofill material and post-treatment follow-up vistis will be conducted for 1 year. This is a single-arm study with no comparison groups.

CONDITIONS

Official Title

A Study to Assess the Clinical Success of Root Canal Treatment Using Novel Obturation Material.

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18-75 years with ASA classification 1 or 2
  • Patients who agreed to participate and have signed informed consent
  • Patients presenting with symptomatic or asymptomatic apical periodontitis with radiographic lesion over 1.5 mm
  • Mature tooth with closed apex
  • Tooth that has never been treated with root canal therapy
Not Eligible

You will not qualify if you...

  • Patients with pre-existing health or oral conditions that place them at risk during the trial
  • Patients with generalized untreated periodontal disease
  • Patients who have taken analgesics within past 3 days or antibiotics within last 1 month
  • Uncooperative patients
  • Teeth with immature apices, root resorption, or needing extensive prosthetic rehabilitation
  • Teeth that cannot be restored or are difficult to access (e.g., wisdom teeth)
  • Teeth with insufficient periodontal support
  • Teeth with poor prognosis for root canal treatment (deep root caries, large root resorption, open apex cases)
  • Fractured teeth
  • Local anatomical factors making root end inaccessible
  • Presence of fractured instrument in the root canal
  • Pregnant women
  • Patients unable to understand the study procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medipol University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

A

Anupama Tripathi

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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