Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07273149

A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting

Led by HALEON · Updated on 2026-04-21

375

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this decentralised study in a real-world setting is to assess the effectiveness of a marketed denture adhesive (Poligrip Power Max Hold + Seal) in preventing food entrapment under dentures (self-assessed). The study will evaluate participants perceived food occlusion of a marketed denture adhesive over three weeks compared to no adhesive use over three weeks in a real-world setting.

CONDITIONS

Official Title

A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant has signed informed consent before any assessments
  • Participants of any gender
  • Participants aged 18 years or older at screening
  • Willing and able to follow all study procedures and restrictions
  • In good general and mental health with no significant medical or oral conditions impacting safety or study outcomes
  • Habitual wearer of partial or full dentures for most waking hours
  • Self-assessed relatively well-fitted dentures
  • Resides in the United States excluding Hawaii and Alaska
Not Eligible

You will not qualify if you...

  • Employees involved in the study or their immediate families, including those of Lindus Health or Haleon
  • Participation in other investigational studies within 30 days before or during this study
  • Previous enrollment in this study
  • Recent or current treatment for periodontal or gum disease within 6 months
  • Diagnosed active periodontitis, candida infection, or active tooth decay
  • Chronic or severe painful conditions requiring frequent pain medication use
  • Significant oral abnormalities affecting study participation
  • Acute or chronic medical or psychiatric conditions affecting safety or study integrity
  • Diagnosed xerostomia or medications causing dry mouth
  • Known intolerance or allergy to study materials or ingredients
  • History of alcohol or substance abuse within the past year
  • History of swallowing difficulties or choking
  • Any denture adjustments or treatments altering fit during the study
  • Current or prior use of bisphosphonate drugs
  • Planned surgery during the study period
  • Inability to read and understand English
  • Investigator's judgment deeming participant unsuitable for the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Lindus Health (virtual site)

Boston, Massachusetts, United States, 02111

Actively Recruiting

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Research Team

H

Haleon Response Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting | DecenTrialz