Actively Recruiting
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
Led by argenx · Updated on 2026-05-08
160
Participants Needed
43
Research Sites
279 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this study is to demonstrate the efficacy and safety of empasiprubart in adults with CIDP. The study consists of a part A where participants will either receive empasiprubart or placebo for 24 weeks (6 months). Following part A, participants will enter part B in which all participants will receive empasiprubart for 96 weeks (24 months). More information can be found here: https://clinicaltrials.argenx.com/emnergize
CONDITIONS
Official Title
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meets criteria for CIDP based on EAN/PNS Task Force CIDP guidelines, second revision (2021)
- Has typical CIDP or one of the following CIDP variants: motor CIDP, multifocal CIDP, focal CIDP, or distal CIDP
- Has residual disability and active disease
- Has not received previous treatment for CIDP, or has stopped receiving CIDP treatment, or is currently receiving CIDP treatment
- Willing to discontinue current CIDP treatment before starting the study medication and switch to the study drug
You will not qualify if you...
- Meets criteria for possible CIDP based on EAN/PNS Task Force CIDP guidelines, second revision (2021)
- Has sensory CIDP, including sensory-predominant CIDP
- Has polyneuropathy caused by other conditions
- Has a clinical diagnosis of systemic lupus erythematosus (SLE)
- Has used other long-acting immunomodulatory treatments or has had total lymphoid irradiation or bone marrow transplantation at any time
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 43 locations
1
Samir Macwan, M.D., Inc. (S corporation)
Rancho Mirage, California, United States, 92270
Actively Recruiting
2
Colorado Springs Neurological Associates
Colorado Springs, Colorado, United States, 80907
Actively Recruiting
3
Medstar Health Research Institute
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
4
Gables Neurology
Miami, Florida, United States, 33133
Actively Recruiting
5
Aqualane Clinical Research
Naples, Florida, United States, 34105
Actively Recruiting
6
Paradigm Health System
Slidell, Louisiana, United States, 70458
Actively Recruiting
7
Penn Medicine University City
Philadelphia, Pennsylvania, United States, 19104-5545
Actively Recruiting
8
National Neuromuscular Research Institute
Austin, Texas, United States, 78756
Actively Recruiting
9
NeuroCarePlus
Houston, Texas, United States, 77094
Actively Recruiting
10
Universitätsklinikum AKH Wien
Vienna, Austria, 1090
Actively Recruiting
11
University Multiprofile Hospital for Active Treatment
Pleven, Bulgaria, 5803
Actively Recruiting
12
Medical Center Medika 2005 - Branch Sofia
Sofia, Bulgaria, 1164
Actively Recruiting
13
University Multiprofile Hospital for Active Treatment Aleksandrovska EAD
Sofia, Bulgaria, 1431
Actively Recruiting
14
University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD
Sofia, Bulgaria, 1606
Actively Recruiting
15
Peking University First Hospital - Changqiao Campus
Beijing, China, 100034
Actively Recruiting
16
Guangdong Provincial Hospital of Chinese Medicine
Guangzhou, China, 510120
Actively Recruiting
17
Nanfang Hospital Southern Medical University
Guangzhou, China, 510515
Actively Recruiting
18
Xi'an Gaoxin Hospital
Xi'an, China, 710075
Actively Recruiting
19
Fakultni nemocnice Brno
Brno, Czechia, 625 00
Actively Recruiting
20
Astra Kliinik
Tallinn, Estonia, 11315
Actively Recruiting
21
High Technology Hospital MedCenter Ltd
Batumi, Georgia, 6000
Actively Recruiting
22
First Medical Clinic LLC
Batumi, Georgia
Actively Recruiting
23
Petre Sarajishvili Institute of Neurology
Tbilisi, Georgia, 0112
Actively Recruiting
24
Aleksandre Aladashvili Clinic
Tbilisi, Georgia, 102
Actively Recruiting
25
Curatio JSC
Tbilisi, Georgia, 114
Actively Recruiting
26
LTD New Hospitals
Tbilisi, Georgia, 114
Actively Recruiting
27
Geo Hospitals
Tbilisi, Georgia, 144
Actively Recruiting
28
Jo Ann Medical Center
Tbilisi, Georgia, 159
Actively Recruiting
29
IRCCS Istituto delle Scienze Neurologiche di Bologna
Bologna, Italy, 40139
Actively Recruiting
30
Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCS
Pavia, Italy, 27100
Actively Recruiting
31
Seirei Hamamatsu Hospital
Hiroshima, Japan, 430-8558
Actively Recruiting
32
Southern TOHOKU Medical Clinic
Kōriyama, Japan, 963-8052
Actively Recruiting
33
Saga University Hospital
Saga, Japan, 849-0937
Actively Recruiting
34
Centrum Medyczne Neurologia Slaska
Katowice, Poland, 40-689
Actively Recruiting
35
SP ZOZ Szpital Uniwersytecki w Krakowie
Krakow, Poland, 30-688
Actively Recruiting
36
S.C. Neurocity S.R.L
Bucharest, Romania
Actively Recruiting
37
SC Clubul Sanatatii SRL
Campulung Muscel, Romania, 115100
Actively Recruiting
38
Spitalul Judetean de Urgenta Deva
Deva, Romania, 330084
Actively Recruiting
39
Univerzitna nemocnica MARTIN
Martin, Slovakia, 036 59
Actively Recruiting
40
Nemocnica s poliklinikou S. Kukuru a.s. - Pentahospitals
Michalovce, Slovakia, 071 01
Actively Recruiting
41
Penta Hospitals SK, a.s. - Rimavská Sobota
Rimavská Sobota, Slovakia, 979 01
Actively Recruiting
42
Seoul National University Hospital
Seoul, South Korea, 03080
Actively Recruiting
43
Korea University Guro Hospital
Seoul, South Korea, 08308
Actively Recruiting
Research Team
S
Sabine Coppieters, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here