Actively Recruiting

Age: 50Years - 90Years
All Genders
Healthy Volunteers
NCT07174869

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Led by Indivi AG · Updated on 2025-09-16

55

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to evaluate the functionality and usability of Indivi mobile application-based cognitive activities in people with mild cognitive impairment/mild Alzheimer's disease (PwMCI/AD) and healthy controls (HC). This application uses a dynamic difficulty adjustment (DDA) system that customizes the level of the cognitive activities to each user. The main questions it aims to answer are: * Does the DDA system reach a stable difficulty level at the same rate for both PwMCI/AD and HC? * Is the stable difficulty level reached by the DDA system different for PwMCI/AD compared to HC? Researchers will also compare cognitive activities results and other aspects of the mobile application's performance to see if the application can validly distinguish between the two groups. Participants will use the Indivi mobile application, with its embedded DDA system, for a 6-week period.

CONDITIONS

Official Title

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Who Can Participate

Age: 50Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant is part of BU-ADRC cohort.
  • Participant is diagnosed with MCI, mild AD, or classified as healthy control per BU-ADRC with data obtained less than 2 years before inclusion.
  • Participant is between 50 and 90 years old.
  • Participant is able to use a smartphone.
  • Participant has sufficient knowledge of the English language.
  • Participant is able to and intends to follow the study procedures.
  • Informed consent is provided as documented by signature.
Not Eligible

You will not qualify if you...

  • Participant has any neurological condition contributing to cognitive impairment beyond MCI or AD.
  • Participant has psychiatric diagnosis or symptoms (e.g., hallucinations, major depression, or delusions) that may interfere with study procedures.
  • Participant has a history of stroke or seizures within the last 24 months.
  • Participant has a Geriatric Depression Scale score of 8 or higher.
  • Participant has severe visual or hearing impairment interfering with cognitive assessments.
  • Known or suspected non-compliance.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston University School of Medicine

Boston, Massachusetts, United States, 02118

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population | DecenTrialz