Actively Recruiting

Phase Not Applicable
Age: 70Years +
MALE
NCT06824818

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Led by University of Chicago · Updated on 2025-10-01

155

Participants Needed

2

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study seeks to identify if it is feasible to stop Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Therapy in elderly men with prostate cancer. We hypothesize that elderly prostate cancer patients on long term androgen ablation with LHRH agonists will be permanently castrated and do not require ongoing LHRH agonist therapy. Participants will be monitored by testosterone testing throughout study.

CONDITIONS

Official Title

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Who Can Participate

Age: 70Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Prostate cancer with more than 3 years of LHRH agonist therapy
  • Age 70 years or older
  • ECOG performance status of 2 or less
  • Baseline testosterone level less than 20 ng/ml
  • No prior chemotherapy or Lu-PSMA unless survival predictions are favorable
  • Ability to understand and sign informed consent
Not Eligible

You will not qualify if you...

  • None

AI-Screening

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Trial Site Locations

Total: 2 locations

1

The University of Illinois at Chicago (UIC)

Chicago, Illinois, United States, 60607

Actively Recruiting

2

UChicago Medicine Comprehensive Cancer Center

Chicago, Illinois, United States, 60637

Not Yet Recruiting

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Research Team

C

Clinical Trials Intake

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients | DecenTrialz