Actively Recruiting

Age: 18Years - 64Years
All Genders
NCT06916507

Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)

Led by AbbVie · Updated on 2026-05-13

125

Participants Needed

17

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess how effective foscarbidopa/ foslevodopa is in treating German adult participants at initial stages of advanced Parkinson's disease under routine clinical practice. Foslevodopa/Foscarbidopa is an approved drug for the treatment of Parkinson's Disease. Approximately 125 adult participants who are prescribed Foslevodopa/Foscarbidopa by their doctors will be enrolled across approximately 20 sites in Germany. Participants will receive Foslevodopa/Foscarbidopa subcutaneous infusion as prescribed by their physician. Participants will be followed for up to 12 months. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

CONDITIONS

Official Title

Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)

Who Can Participate

Age: 18Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of levodopa-responsive idiopathic Parkinson's disease
  • Eligible for foscarbidopa/foslevodopa therapy according to local approved label
  • Adult male or female between 18 and 64 years old
  • Motor fluctuations started 3 years ago or less
  • Hoehn and Yahr stage less than 3 while on medication
  • Decision to treat with foscarbidopa/foslevodopa made by clinician before approaching participant
Not Eligible

You will not qualify if you...

  • Previous use of any device-aided therapy
  • Any condition listed as a contraindication in the local foscarbidopa/foslevodopa label
  • Mini mental state examination (MMSE) score less than 24

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 17 locations

1

Universitaetsklinikum Heidelberg /ID# 274164

Heidelberg, Baden-Wurttemberg, Germany, 69120

Actively Recruiting

2

Universitaetsklinikum Tuebingen /ID# 275828

Tübingen, Baden-Wurttemberg, Germany, 72076

Actively Recruiting

3

Praxis Prof. Kassubek/Prof. Riecker /ID# 274165

Ulm, Baden-Wurttemberg, Germany, 89073

Actively Recruiting

4

Parkinson-Klinik Ortenau GmbH&Co KG /ID# 274161

Wolfach, Baden-Wurttemberg, Germany, 77709

Actively Recruiting

5

Universitaetsklinikum Erlangen /ID# 280831

Erlangen, Bavaria, Germany, 91054

Actively Recruiting

6

Klinikum Ingolstadt /ID# 280573

Ingolstadt, Bavaria, Germany, 85049

Actively Recruiting

7

Klinikum der Universitaet Muenchen Grosshadern /ID# 274168

Munich, Bavaria, Germany, 81337

Actively Recruiting

8

Klinikum Ernst von Bergmann /ID# 274176

Potsdam, Brandenburg, Germany, 14467

Actively Recruiting

9

Universitaetskliniken Giessen und Marburg /ID# 274224

Marburg, Hesse, Germany, 35043

Actively Recruiting

10

Knappschaftskrankenhaus Bottrop /ID# 274284

Bottrop, North Rhine-Westphalia, Germany, 46242

Actively Recruiting

11

Cellitinnen-NTC Neurologisches Therapiecentrum /ID# 277865

Cologne, North Rhine-Westphalia, Germany, 50668

Actively Recruiting

12

Klinikum Lippe Detmold /ID# 279451

Detmold, North Rhine-Westphalia, Germany, 32756

Actively Recruiting

13

Klinikum Dortmund Klinikzentrum Mitte /ID# 280222

Dortmund, North Rhine-Westphalia, Germany, 44137

Actively Recruiting

14

Universitaetsklinikum Carl Gustav Carus Dresden /ID# 274167

Dresden, Saxony, Germany, 01307

Actively Recruiting

15

Krankenhaus Martha-Maria Halle-Dölau /ID# 274174

Halle, Saxony-Anhalt, Germany, 06120

Actively Recruiting

16

Praxis MD Oehlwein /ID# 274222

Gera, Thuringia, Germany, 07551

Actively Recruiting

17

Asklepios Fachklinikum Stadtroda /ID# 274162

Stadtroda, Thuringia, Germany, 07646

Actively Recruiting

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Research Team

M

Medical Information Germany

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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