Actively Recruiting

Phase 1
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07377396

A Study to Assess the Safety of ARGX-124 in Healthy Volunteers

Led by argenx · Updated on 2026-03-06

104

Participants Needed

1

Research Sites

48 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to assess the safety of ARGX-124 in healthy adults. Another aim is to measure the amount of ARGX-124 in the blood over time to learn how it acts and moves in the body and how the immune system responds to it. Participants will remain in the study for up to approximately 23 weeks.

CONDITIONS

Official Title

A Study to Assess the Safety of ARGX-124 in Healthy Volunteers

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Is aged 18 to 65 years and meets the local legal age of consent when signing the consent form
  • Is male or a female who is postmenopausal or surgically sterilized (nonchildbearing potential)
  • Has a body weight between 50 and 120 kg
  • Has a body mass index (BMI) between 18 and 30.5 kg/m2
Not Eligible

You will not qualify if you...

  • Has any current or past medical or psychiatric condition that could affect study results or increase risk
  • Has IgG levels less than 6.0 g/L at screening
  • Has a history or current condition causing immunosuppression
  • Previously participated in a clinical study involving ARGX-124, ARGX-213, or efgartigimod and received the study drug

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Altasciences

Montreal, Canada, H3P 3P1

Actively Recruiting

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Research Team

S

Sabine Coppieters, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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A Study to Assess the Safety of ARGX-124 in Healthy Volunteers | DecenTrialz