Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT07325136

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer

Led by Bristol-Myers Squibb · Updated on 2026-05-07

240

Participants Needed

11

Research Sites

168 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess the safety and tolerability of BMS-986525 alone and in combination with Nivolumab in participants with Relapsed/Refractory Small Cell Lung Cancer

CONDITIONS

Official Title

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have histologically or cytologically documented relapsed/refractory small cell lung cancer (R/R-SCLC).
  • Participants must have received at least 1 platinum-based chemotherapy regimen as per locally approved drug labels and institutional guidelines.
  • In countries where standard of care first line systemic treatment includes platinum containing chemotherapy in combination with anti-PD-(L)1 therapy, it is required that participants have progressed on, are ineligible for or not have access to an anti-PD- (L)1 therapy.
Not Eligible

You will not qualify if you...

  • Participants must not have any untreated CNS metastases.
  • Participants must not have an active, known or suspected autoimmune disease.
  • Participants must not have had a prior organ or tissue allograft.
  • Other protocol-defined Inclusion/Exclusion criteria apply.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 11 locations

1

Local Institution - 0011

Detroit, Michigan, United States, 48201

Not Yet Recruiting

2

Local Institution - 0026

Buffalo, New York, United States, 14263

Not Yet Recruiting

3

Duke Cancer Institute

Durham, North Carolina, United States, 27710

Actively Recruiting

4

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106

Actively Recruiting

5

SCRI Oncology Partners

Nashville, Tennessee, United States, 37203

Actively Recruiting

6

Local Institution - 0001

Rozzano, Milano, Italy, 20089

Not Yet Recruiting

7

Local Institution - 0020

Hirakata, Osaka, Japan, 573-1191

Not Yet Recruiting

8

Local Institution - 0018

Chuo-ku, Tokyo, Japan, 104-0045

Not Yet Recruiting

9

Local Institution - 0023

Timișoara, Timiș County, Romania, 300239

Not Yet Recruiting

10

Local Institution - 0003

Craiova, Romania, 200347

Not Yet Recruiting

11

Local Institution - 0009

Madrid, Spain, 28041

Not Yet Recruiting

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Research Team

B

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

CONTACT

F

First line of the email MUST contain NCT # and Site #.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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