Actively Recruiting
A Study to Assess Treatment Patterns and Treatment Adherence in Early HER2-positive Breast Cancer Participants After Treatment Decentralization
Led by Hoffmann-La Roche · Updated on 2026-05-08
100
Participants Needed
10
Research Sites
118 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this study is to evaluate the impact of a decentralized treatment model on treatment adherence in participants with early-stage human epidermal growth factor receptor 2- positive (HER2+) breast cancer (BC). This study has 2 groups: Group 1: Consistent Travel Burden (Cohorts A, C, and D), will include participants whose adjuvant therapy location does not increase their travel requirements, and Group 2: Increased Travel Burden (Cohort B), will include participants who must travel from a secondary center to a tertiary center to receive their adjuvant therapy.
CONDITIONS
Official Title
A Study to Assess Treatment Patterns and Treatment Adherence in Early HER2-positive Breast Cancer Participants After Treatment Decentralization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of stage II and III HER2-positive early breast cancer according to European Society For Medical Oncology guidelines
- Underwent curative-intent surgical resection for breast cancer
- Histologically confirmed HER2-positive breast cancer as per American Society of Clinical Oncology/College of American Pathologists guidelines before or after surgery
You will not qualify if you...
- Any medical or psychiatric condition that would affect ability to provide informed consent or complete study questionnaires
- Prior neoadjuvant or adjuvant therapy for HER2-positive breast cancer received at a center other than the 10 participating study sites
- Participants from specified secondary centers who started neoadjuvant therapy at the tertiary center instead of their local secondary center
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 10 locations
1
Health Centre Loznica
Loznica, Bolnička 65, Serbia, 15300
Actively Recruiting
2
General Hospital Požarevac
Požarevac, Bratstva Jedinstva 135, Serbia, 12000
Actively Recruiting
3
Healthcare Centre Bor
Bor, Dragiše Mišovića 1, Serbia, 19210
Actively Recruiting
4
Health Centre Kladovo
Kladovo, Dunavska 1-3, Serbia, 19320
Actively Recruiting
5
Health Centre ''Sveti Luka'' Smederevo
Smederevo, Knez Mihailova 51, Serbia, 11300
Actively Recruiting
6
General Hospital Pančevo
Pančevo, Miloša Trebinjca 11, Serbia, 26000
Actively Recruiting
7
Institute for Onocology and Radiology of Serbia
Belgrade, Pasterova 14, Serbia, 11000
Actively Recruiting
8
General Hospital "Dr Laza K. Lazarevic" Sabac
Šabac, Popa Karana 2-4, Serbia, 15000
Actively Recruiting
9
Health Centre Valjevo
Valjevo, Sinđelićeva 62, Serbia, 14000
Actively Recruiting
10
General Hospital ''Stefan Visoki'' Smederevska Palanka
Smederevska Palanka, Vuka Karadžića 147, Serbia, 11420
Actively Recruiting
Research Team
R
Reference Study ID Number: ML46477 https://forpatients.roche.com/
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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