Evaluating Acupuncture Effects on Parkinsons Disease Patients with Chronic Appendicitis in a Double-Blind Randomized Study

What this Trial Is About

Parkinsons disease PD is a condition where symptoms worsen over time, and medications may become less effective, significantly lowering patients quality of life. Recent findings suggest a close link between PD symptoms and intestinal health, especially in patients with chronic appendicitis. Acupuncture targeting points related to constipation and chronic appendicitis has shown promise in improving both motor and non-motor symptoms of PD, such as anxiety, depression, sleep disturbances, and cognitive dysfunction. This study aims to further understand acupunctures role in treating PD comprehensively, particularly focusing on intestinal acupuncture. Participants in this randomized, double-blind trial will receive acupuncture treatment at specific points including Tianshu, Zusanli, Hegu, Taichong, Shangjuxu, Jigou, Zhaohai, Lanwei, and Shousanli. The interventions involve comfort needle and comfort embedding needle techniques. The study compares an experimental acupuncture group with a control group receiving sham acupuncture, where the needle only touches the skin without penetration. Treatment schedules and methods are designed to assess acupunctures effects on PD symptoms in patients with chronic appendicitis. During the study, participants will be evaluated using the MDS Unified Parkinsons Disease Rating Scale III over three months to measure motor symptom changes. Researchers will monitor symptom improvements and adverse events while ensuring participants maintain stable anti-PD medication if used. The trial includes informed consent, clinical examinations, imaging for appendicitis confirmation, and other assessments to ensure safety and data accuracy. The total participation spans the treatment and follow-up periods up to the studys end in 2026.

A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis