Actively Recruiting
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
Led by The First Affiliated Hospital of University of Science and Technology of China · Updated on 2024-03-12
84
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients. Recent studies have found that these PD symptoms are closely related to the intestine. For several cases of PD syndrome patients complicated with chronic appendicitis, our research group conducted acupuncture on points related to constipation and chronic appendicitis, and found that constipation and related motor symptoms of patients could be significantly improved. Clinical studies have shown that acupuncture also has a certain therapeutic effect on non-motor symptoms of Parkinson's disease, such as anxiety and depression, decreased olfactory function, sleep disorders, constipation, early skeletal muscle pain, cognitive dysfunction, etc., which can delay the progression of the disease and improve the quality of life of patients. Starting from intestinal acupuncture, this project further clarified the role of acupuncture treatment in the comprehensive treatment of PD
CONDITIONS
Official Title
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients presenting with bradykinesia, combined with resting tremor and/or myotonia
- Chronic appendicitis confirmed by appendix CT evaluated by two experts
- Patients and their guardians provide informed consent and sign consent forms
- Normal blood clotting function
- Stable use of oral anti-PD drugs for at least 2 weeks before enrollment, if applicable
You will not qualify if you...
- Treatment with dopamine blockers or depleters consistent with drug-induced parkinsonism
- Normal presynaptic dopaminergic system on neuroimaging
- Severe brain trauma or complex craniotomy within 5 years before enrollment
- Diagnosed cognitive disorders not related to Parkinson's, such as Alzheimer's or frontotemporal dementia
- Severe neuropsychiatric disorders including epilepsy, bipolar disorder, or major depression
- Serious systemic diseases, consciousness disorders, stroke, severe heart disease, diabetes, liver or kidney disease, severe vision or hearing impairments
- Severe organic or functional swallowing difficulties
- Inability to complete study visits and examinations as required by the protocol
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of University of Science and Technology of China
Hefei, Anhui, China, 230001
Actively Recruiting
Research Team
Y
Yuhua Chen, M.M.S.
CONTACT
C
Chao Han, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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