Efficacy and Safety of Acute Phase Intensive Electrical Muscle Stimulation in Frail Older Patients with Acute Heart Failure: Results from the ACTIVE-EMS Trial.
Shinya Tanaka, Kentaro Kamiya, Yuya Matsue...
https://pubmed.ncbi.nlm.nih.gov/35448075Actively Recruiting
Age: 60Years +
All Genders
ID06281275
A Study on the Association Between Frailty and Acute Postoperative Pain in Elderly Patients Undergoing Thoracoscopic Surgery and an Investigation of the Mechanisms Involved
Led by Huazhong University of Science and Technology · Updated on 2024-06-21
78
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the relationship between frailty and acute postoperative pain in elderly patients undergoing thoracoscopic surgery. Frailty is a condition marked by decreased physiological reserve and increased vulnerability to stressors, common in older adults. This study aims to better understand how frailty affects pain after surgery and its underlying mechanisms, potentially offering new ways to reduce pain and improve quality of life and mental health in this population. The study includes elderly patients aged 60 and above who have thoracoscopic surgery under general anesthesia with postoperative patient-controlled analgesia for 48 hours. Researchers will observe and record pain levels at rest and during coughing over the first 48 hours after surgery using the Numerical Rating Scale (NRS). Additional measures include the use and frequency of patient-controlled analgesia pumps. No specific interventions or treatment groups are assigned since this is an observational study. Participants will be monitored for their pain intensity and frailty status before and after surgery. Data collection includes pain assessments at rest and while coughing during the first two days post-surgery, as well as tracking analgesia pump consumption. The study runs from February to October 2024. The goal is to clarify how frailty influences postoperative pain, contributing to better management and outcomes for elderly thoracoscopic surgery patients.
CONDITIONS
Brief Title
A Study of the Association Between Frailty and Acute Postoperative Pain in Elderly Thoracoscopic Surgery Patients
Who Can Participate
Age: 60Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patients undergoing thoracic surgery under general anesthesia with 48 hours of postoperative patient-controlled analgesia
- Age 60 years or older
- ASA class I to III
- Signed informed consent
- Patients undergoing thoracoscopic surgery
You will not qualify if you...
- Patients who refuse to participate
- Drug dependence
- Difficulty cooperating with communication or verbal communication problems
- Unable to assess frailty before surgery or pain after surgery
- Failure to provide a compliant fecal sample at the agreed time
- Antibiotic treatment within the last month
- Intestinal dysfunction such as irritable bowel syndrome, inflammatory bowel disease, or chronic diarrhea
- Certain metabolic disorders like thyroid dysfunction or diabetes affecting microbial community structure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - 2 days
Participants undergo thoracoscopic surgery and receive patient-controlled analgesia for 48 hours after surgery to manage pain.
Continuous monitoring during hospital stay
Post-operative Follow-up
Duration - Up to 48 hours after surgery
Participants are observed for pain levels and related outcomes after surgery to understand the association between frailty and acute postoperative pain.
Assessments during hospital stay
Trial Site Locations
Total: 1 location
1
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
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Research Team
X
Xianwei Zhang, Doctor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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