Actively Recruiting

Phase 3
Age: 1Year - 18Years
All Genders
NCT03773965

A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

Led by Eli Lilly and Company · Updated on 2026-05-12

190

Participants Needed

80

Research Sites

638 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The reason for this study is to see if the study drug baricitinib is safe and effective in the treatment of JIA in participants ages 1 to 17. This study is for participants that have been enrolled in studies I4V-MC-JAHV (NCT03773978) or I4V-MC-JAHU.

CONDITIONS

Official Title

A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

Who Can Participate

Age: 1Year - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have completed a previous study of baricitinib for the treatment of JIA.
Not Eligible

You will not qualify if you...

  • Participants must not have had a permanent discontinuation of baricitinib in the prior study.
  • Participants must have not developed an allergy to baricitinib.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 80 locations

1

Instituto CAICI SRL

Rosario, Argentina, S2000

Actively Recruiting

2

Centro de Investigaciones Médicas Tucuman

SAN M. de Tucuman, Argentina, T4000AXL

Actively Recruiting

3

Royal Children's Hospital

Melbourne, Australia, 3052

Not Yet Recruiting

4

Perth Children's Hospital

Perth, Australia, 6009

Not Yet Recruiting

5

The Children's Hospital at Westmead

Westmead, Australia, 2145

Active, Not Recruiting

6

Landeskrankenhaus Bregenz

Bregenz, Austria, 6900

Completed

7

Cliniques universitaires Saint-Luc

Brussels, Belgium, 1200

Completed

8

UZ Gent

Ghent, Belgium, 9000

Actively Recruiting

9

UZ Leuven

Leuven, Belgium, 3000

Actively Recruiting

10

Faculdade de Medicina da UNESP

Botucatu, Brazil, 18618-686

Actively Recruiting

11

Universidade Federal de Sao Paulo

São Paulo, Brazil, 04024-002

Actively Recruiting

12

Instituto da Crianca do Hospital das Clinicas da FMUSP

São Paulo, Brazil, 05403-000

Actively Recruiting

13

Beijing Children's hospital, Capital Medical University

Beijing, China, 100045

Active, Not Recruiting

14

The Children's Hospital of Chongqing Medical University

Chongqing, China, 400065

Active, Not Recruiting

15

Childrens Hospital of Nanjing Medical University

Nanjing, China, 210008

Actively Recruiting

16

Children's Hospital of Soochow University

Suzhou, China, 215025

Actively Recruiting

17

Detska nemocnice FN Brno

Brno, Czechia, 613 00

Actively Recruiting

18

Vseobecna fakultni nemocnice v Praze

Prague, Czechia, 12808

Actively Recruiting

19

Fakultni nemocnice Motol

Prague, Czechia, 150 06

Actively Recruiting

20

Aarhus Universitetshospital, Skejby

Aarhus, Denmark, 8200

Actively Recruiting

21

Hospices Civils de Lyon - Hôpital Femme Mère Enfant

Bron, France, 69500

Actively Recruiting

22

Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre

Le Kremlin-Bicêtre, France, 94270

Actively Recruiting

23

Centre Hospitalier Universitaire de Nîmes - Hôpital Universitaire Carémeau

Nîmes, France, 30029

Actively Recruiting

24

Hôpital Universitaire Necker Enfants Malades

Paris, France, 75015

Actively Recruiting

25

Centre Hospitalier Universitaire de Poitiers

Poitiers, France, 86021

Actively Recruiting

26

Helios Klinikum Berlin-Buch

Berlin, Germany, 13125

Active, Not Recruiting

27

Charité Campus Virchow-Klinikum

Berlin, Germany, 13353

Completed

28

Praxis Kinder- und Jugendrheumatologie Dr. Ivan Foeldvari

Hamburg, Germany, 22081

Active, Not Recruiting

29

Universitätsklinikum Heidelberg

Heidelberg, Germany, 69115

Completed

30

Asklepios Klinik Sankt Augustin

Sankt Augustin, Germany, 53757

Active, Not Recruiting

31

Universitaetsklinikum Tuebingen

Tübingen, Germany, 72076

Active, Not Recruiting

32

Sri Ramachandra MedicaL College & Research Institute

Chennai, India, 600116

Completed

33

Sir Ganga Ram Hospital

New Delhi, India, 110060

Actively Recruiting

34

Christian Medical College Vellore

Vellore, India, 632004

Actively Recruiting

35

Rambam Health Care Campus

Haifa, Israel, 3109601

Actively Recruiting

36

Meir Medical Center

Kfar Saba, Israel, 4428164

Actively Recruiting

37

Schneider Children's Medical Center

Petah Tikva, Israel, 49202

Actively Recruiting

38

Sheba Medical Center

Ramat Gan, Israel, 5262100

Actively Recruiting

39

Azienda Ospedaliera Spedali Civili di Brescia

Brescia, Italy, 25123

Actively Recruiting

40

Azienda Sanitaria Locale n. 2 - Lanciano Vasto Chieti

Chieti, Italy, 66100

Completed

41

IRCCS Istituto Giannina Gaslini

Genova, Italy, 16147

Actively Recruiting

42

Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO

Milan, Italy, 20122

Not Yet Recruiting

43

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

Milan, Italy, 20122

Completed

44

University of Naples Federico II

Naples, Italy, 80131

Actively Recruiting

45

Azienda di Rilievo Nazionale e Alta Specializzazione Civico Di Cristina Benfratelli

Palermo, Italy, 90127

Not Yet Recruiting

46

Ospedale Infantile Burlo Garofolo

Trieste, Italy, 34137

Actively Recruiting

47

Institute of Science Tokyo Hospital

Bunkyō, Japan, 113-8519

Actively Recruiting

48

Chiba Children's Hospital

Chiba, Japan, 266-0007

Actively Recruiting

49

Kagoshima University Hospital

Kagoshima, Japan, 890-8520

Actively Recruiting

50

Kanazawa University Hospital

Kanazawa, Japan, 920-8641

Actively Recruiting

51

Niigata University Medical & Dental Hospital

Niigata, Japan, 951-8520

Actively Recruiting

52

Saitama Children's Medical Center

Saitama-shi, Japan, 330 8777

Actively Recruiting

53

Miyagi Children's Hospital

Sendai, Japan, 989-3126

Actively Recruiting

54

Tokyo Women's Medical University Hospital

Shinjuku-ku, Japan, 162-8666

Actively Recruiting

55

Osaka Medical and Pharmaceutical University Hospital

Takatsuki, Japan, 569-8686

Actively Recruiting

56

Kanagawa Children's Medical Center

Yokohama, Japan, 232-8555

Actively Recruiting

57

Yokohama City University Hospital

Yokohama, Japan, 236-0004

Actively Recruiting

58

Investigacion y Biomedicina de Chihuahua

Chihuahua City, Mexico, 31000

Actively Recruiting

59

Instituto de Investigaciones Clínicas para la Salud

Durango, Mexico, 34000

Actively Recruiting

60

Crea de Guadalajara

Guadalajara, Mexico, 44600

Actively Recruiting

61

Clinstile, S.A. de C.V.

México, Mexico, 6700

Actively Recruiting

62

Hospital Universitario "Dr. Jose Eleuterio Gonzalez"

Monterrey, Mexico, 66460

Actively Recruiting

63

Wojewódzki Specjalistyczny Szpital Dziecięcy im. św. Ludwika w Krakowie

Krakow, Poland, 31-503

Actively Recruiting

64

Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi

Lodz, Poland, 91-738

Actively Recruiting

65

Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji

Warsaw, Poland, 02-637

Actively Recruiting

66

Federal State Budgetary Scientific Institution Research Institute Rheumatology named after V.A.Nasonova

Moscow, Russia, 115522

Completed

67

Scientific Center of Children's Health

Moscow, Russia, 119991

Completed

68

Hospital Sant Joan de Déu

Esplugues de Llobregat, Spain, 8950

Actively Recruiting

69

Hospital Infantil Universitario Niño Jesús

Madrid, Spain, 28009

Actively Recruiting

70

Hospital Universitario Ramón y Cajal

Madrid, Spain, 28034

Actively Recruiting

71

Hospital Universitario La Paz

Madrid, Spain, 28046

Actively Recruiting

72

Hospital Universitario Virgen Del Rocio

Seville, Spain, 41013

Not Yet Recruiting

73

Hospital Universitari i Politecnic La Fe

Valencia, Spain, 46026

Actively Recruiting

74

Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine

Istanbul, Turkey (Türkiye), 34098

Actively Recruiting

75

9 Eylul University Hospital

Izmir, Turkey (Türkiye), 35340

Actively Recruiting

76

Bristol Royal Hospital for Children

Bristol, United Kingdom, BS2 8BJ

Actively Recruiting

77

Alder Hey Children's Hospital

Liverpool, United Kingdom, L14 5AB

Actively Recruiting

78

Great Ormond Street Hospital For Children NHS Foundation Trust

London, United Kingdom, WC1N 3JH

Actively Recruiting

79

Oxford University Hospitals - Nuffield Orthopaedic Centre

Oxford, United Kingdom, OX3 7LD

Actively Recruiting

80

Sheffield Children's Hospital

Sheffield, United Kingdom, S10 2TH

Actively Recruiting

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Research Team

T

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

CONTACT

P

Physicians interested in becoming principal investigators please contact

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis | DecenTrialz