Actively Recruiting

Phase 2
Age: 18Years - 65Years
All Genders
NCT06911203

A Study of BGM0504 in Participants With Obesity

Led by BrightGene Bio-Medical Technology Co., Ltd. · Updated on 2025-10-28

90

Participants Needed

1

Research Sites

40 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the efficacy and safety of BGM0504 compared with Tirzepatide in adult participants who have obesity without diabetes after 26 weeks of treatment.

CONDITIONS

Official Title

A Study of BGM0504 in Participants With Obesity

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able and willing to provide written informed consent.
  • Male or female aged 18 to 65 years at consent.
  • Body mass index (BMI) between 35.0 and 45.0 kg/m2 at screening.
  • Stable diet and exercise control for at least 3 months before screening with self-reported weight change within ±5%.
Not Eligible

You will not qualify if you...

  • History of chronic or acute pancreatitis.
  • History of severe drug allergy or specific allergic diseases.
  • Family or personal history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.
  • History of malignant tumors except certain in situ carcinomas or specific skin cancers.
  • Suspected or confirmed history of alcohol or drug abuse.
  • Chronic infections like hepatitis B, hepatitis C, HIV, or syphilis that could interfere with the study.
  • Donation or loss of 400 mL or more blood within 3 months before screening or during study.
  • Pregnant or lactating women.
  • Any other disorder or unwillingness that might jeopardize safety or compliance as judged by the investigator.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China, 100044

Actively Recruiting

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Research Team

L

Linong Ji

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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