Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT06697197

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Led by Bristol-Myers Squibb · Updated on 2026-02-03

413

Participants Needed

21

Research Sites

202 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to test the safety and efficacy of BMS-986482 alone and as combination therapy in participants with advanced solid tumors.

CONDITIONS

Official Title

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have a confirmed advanced, unresectable or metastatic solid tumor measurable by RECIST v1.1 and have received, are refractory to, ineligible for, intolerant of, or have refused therapies known to provide clinical benefit.
  • Participants must be 18 years or older or the legal age of consent in their location at the time of signing the consent form.
Not Eligible

You will not qualify if you...

  • History of life-threatening immune-mediated toxicity related to prior T-cell agonist or checkpoint inhibitor therapy, except if unlikely to recur with standard treatment.
  • Any significant acute or chronic medical illness that could interfere with the study treatment or follow-up according to the investigator.
  • Other protocol-defined inclusion or exclusion criteria apply.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 21 locations

1

University of California, Irvine (UCI) Health - UC Irvine Medical Center

Irvine, California, United States, 92612

Actively Recruiting

2

The Angeles Clinic and Research Institute - West Los Angeles Office

Los Angeles, California, United States, 90025

Actively Recruiting

3

Local Institution - 0008

Aurora, Colorado, United States, 80045

Not Yet Recruiting

4

John Theurer Cancer Center at Hackensack University Medical Center

Hackensack, New Jersey, United States, 07601

Actively Recruiting

5

Northwell Health/ RJ Zuckerberg Cancer Center

Lake Success, New York, United States, 11042

Actively Recruiting

6

Levine Cancer Institute

Charlotte, North Carolina, United States, 28204

Actively Recruiting

7

Fred Hutchinson Cancer Center

Seattle, Washington, United States, 98109

Actively Recruiting

8

UZ Gent

Ghent, Oost-Vlaanderen, Belgium, 9000

Actively Recruiting

9

Rigshospitalet

Copenhagen, Capital Region, Denmark, DK-2100

Actively Recruiting

10

Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone

Marseille, Bouches-du-Rhône, France, 13385

Actively Recruiting

11

Gustave Roussy

Villejuif, Paris, France, 94800

Actively Recruiting

12

General Hospital of Athens "Laiko"

Athens, Attikí, Greece, 11527

Actively Recruiting

13

Papageorgiou General Hospital of Thessaloniki

Thessaloniki, Thessaloníki, Greece, 564 29

Actively Recruiting

14

Fondazione IRCCS Istituto Nazionale dei Tumori

Milan, Lombardy, Italy, 20133

Actively Recruiting

15

Istituto Clinico Humanitas

Rozzano, Milano, Italy, 20089

Actively Recruiting

16

Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL)

Amsterdam, North Holland, Netherlands, 1066 CX

Actively Recruiting

17

Erasmus Medisch Centrum

Rotterdam, Netherlands, 3015 GD

Actively Recruiting

18

Hospital Universitari Vall d'Hebron

Barcelona, Barcelona [Barcelona], Spain, 08035

Actively Recruiting

19

Clinica Universidad de Navarra

Pamplona, Navarre, Spain, 31008

Actively Recruiting

20

Hospital Universitario HM Sanchinarro

Madrid, Spain, 28050

Actively Recruiting

21

Karolinska Universitetssjukhuset Solna

Solna, Stockholms Län [se-01], Sweden, 171 64

Actively Recruiting

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Research Team

B

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

CONTACT

F

First line of the email MUST contain NCT # and Site #.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

9

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A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors | DecenTrialz