Actively Recruiting
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Led by Mayo Clinic · Updated on 2026-02-12
50
Participants Needed
1
Research Sites
167 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.
CONDITIONS
Official Title
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Predominant symptoms of gastroesophageal reflux disease including heartburn, regurgitation
- Ability to give appropriate informed consent
You will not qualify if you...
- Prior diagnosis of small intestinal bacterial overgrowth (SIBO)
- Use of proton pump inhibitors (PPIs) or H2 receptor antagonists in the prior 3 months
- Major concomitant illness such as renal, hepatic, rheumatologic, cardiovascular disease, or malignancy
- Antibiotic therapy within one month
- Prior gastrointestinal surgery including esophageal, gastric, and small or large bowel surgery
- Previously diagnosed irritable bowel syndrome or inflammatory bowel disease
- Pregnancy or breastfeeding
- Plans to become pregnant
- Inability to take proton pump inhibitors, including allergy or sensitivity
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic Florida
Jacksonville, Florida, United States, 32224
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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