Actively Recruiting
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-24
150
Participants Needed
7
Research Sites
154 weeks
Total Duration
On this page
Sponsors
M
Memorial Sloan Kettering Cancer Center
Lead Sponsor
A
American Heart Association
Collaborating Sponsor
AI-Summary
What this Trial Is About
The researchers are doing this study to see how well cardiac magnetic resonance imaging (CMR) scans can be used to examine the properties of central venous catheter-associated right atrial clot (RA clot). This could help doctors decide on the best treatment options.
CONDITIONS
Official Title
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients must have pathologically confirmed systemic cancer of any type and stage at time of CMR
- Cardiac mass (CMASS) must be identified on imaging with characteristics defined by established criteria
- Adequate kidney function with creatinine clearance of at least 30 mL/min
- No history of allergic reaction to gadolinium contrast agents or similar compounds
- Adults aged over 18 years with an indwelling central venous catheter for at least 7 days prior to CMR
- Presence of right atrial thrombus confirmed by CMR criteria
- Patients who underwent CMR within past 3 months for cardiac mass evaluation confirming right atrial thrombus are eligible
You will not qualify if you...
- Known pre-existing cardiovascular diseases affecting heart function, including chronic atrial arrhythmias and cardiomyopathies with ejection fraction below 53%
- Restrictive cardiomyopathy such as cardiac amyloidosis or myocardial fibrosis
- Constrictive pericarditis
- Moderate or greater valvular heart disease
- Cardiac neoplastic involvement
- Unable to provide informed consent due to clinical or mental status
- Standard contraindications to MRI, including incompatible metal implants or devices
- Contraindications to gadolinium contrast such as allergy or kidney dysfunction with GFR below 30 mL/min
- Inability to tolerate CMR due to clinical condition, respiratory compromise, or severe claustrophobia
- Pregnant or nursing females
- Vulnerable populations as defined by regulations
- Participants at higher risk due to age, frailty, or emergency conditions
AI-Screening
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Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Consent Only )
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk- Commack (Consent Only)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activites)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States, 11553
Actively Recruiting
Research Team
A
Angel Chan, MD, PhD
CONTACT
A
Adie Friedman, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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