Actively Recruiting
A Study of CD8+ T Cell Imaging During Treatment in People With Non-Small Cell Lung Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2025-08-12
5
Participants Needed
7
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study to learn whether PET/CT (positron emission tomography/computed tomography) scans using an imaging agent (radiotracer) called zirconium Zr 89 crefmirlimab berdoxam is a safe and effective way to identify CD8+ T cells
CONDITIONS
Official Title
A Study of CD8+ T Cell Imaging During Treatment in People With Non-Small Cell Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient must be 18 years of age or older at the time of signing the informed consent.
- Patient has a histologically confirmed diagnosis of metastatic non-small cell lung cancer.
- Patient is enrolled in the engineered TIL cell therapy protocol OBX115-23-01, but has not received the treatment yet.
- Men and women of child-producing potential must use effective double barrier contraceptive methods during the study and up to 30 days after the last administration of the investigational product.
- Patient or legally authorized representative provided signed informed consent, including compliance with study requirements.
- Patient or legally authorized representative provided written authorization for use and disclosure of protected health information.
You will not qualify if you...
- Pregnant or breastfeeding women.
- Patients with a history of splenectomy or significant splenic dysfunction, such as splenomegaly or recurrent infections due to impaired immune function.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering at Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent only)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Consent only)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All protocol activities)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Cancer Center @ Nassau (Consent only)
Uniondale, New York, United States, 11553
Actively Recruiting
Research Team
A
Adam Schoenfeld, MD
CONTACT
A
Alexander Shoushtari, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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