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Study of Heart Function and Blood Flow Changes During General Anesthesia With Echocardiography Monitoring
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-08-10
250
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how general anesthesia affects heart function and blood flow, particularly focusing on people who experience low blood pressure shortly after anesthesia is given. The goal is to better understand the changes in heart pumping and blood flow during surgery. This observational study involves adult patients who require general anesthesia and intubation for surgery, with a planned preparation time before incision. During the study, participants will receive routine anesthetic and perioperative care enhanced by echocardiography and a non-invasive blood pressure cuff to measure blood pressure at intervals of 2.5 to 5 minutes. These measurements will be taken before anesthesia induction, immediately after, and following intubation, continuing for up to 20 minutes total. This approach allows researchers to closely monitor heart function and blood flow changes in real time. Participants will undergo monitoring with echocardiography and blood pressure measurements during the anesthesia induction period. Researchers will assess the proportion of patients who experience low blood pressure within 20 minutes after anesthesia begins. The study does not involve experimental treatments, and all care follows standard surgical procedures. Participation duration includes the anesthesia induction and monitoring period during surgery preparation.
CONDITIONS
Brief Title
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients 18 years of age or older requiring general anesthesia for surgery
- Intubation required for anesthetic management or surgery
- Anticipated preparation time before incision of about 20 minutes
- Baseline mean arterial pressure (MAP) greater than 70 mmHg
You will not qualify if you...
- History of coronary artery disease
- History of cardiac disease including hypertension, arrhythmias, valvular or structural abnormalities
- History of peripheral artery occlusive disease
- Use of beta-blocker medications
- Use of anti-hypertensive medications
- Receiving epidural, spinal, paravertebral, or serratus blocks before surgery
- Need for rapid sequence induction with simultaneous intubation and induction
- Emergency surgery
Research Team
A
Anahita Dabo-Trubelja, MD
G
Gregory Fischer, MD
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