Observational Study on Congenital Bicuspid Aortic Valve in Chinese Patients Aged 14 to 60 Years Tracking Disease Progress and Treatment Outcomes

What this Trial Is About

Researchers are investigating congenital bicuspid aortic valve BAV, a heart condition that may be more common in China than previously recognized. This observational study aims to analyze gene backgrounds, disease progression, and imaging features of young people with BAV, along with their long-term health outcomes. The study hopes to identify individuals at higher risk based on specific gene expression or other clinical characteristics. The study follows a cohort of participants aged 14 to 60 years who have a confirmed diagnosis of BAV through imaging methods such as echocardiography or cardiac magnetic resonance. Participants will be observed over time without receiving experimental treatments. The study will monitor disease progression, including the need for surgical aortic valve replacement SAVR or transcatheter aortic valve replacement TAVR over a five-year period. Participants will undergo regular follow-up visits to assess heart health and disease status using imaging and clinical evaluations. The study will track major adverse cardiovascular events MACE during the five years. Researchers will collect data on patient outcomes, disease progression, and treatment interventions. The total participation duration extends across several years to capture long-term follow-up information.

A Study of Chinese Congenital Bicuspid Aortic Valve