Actively Recruiting
A Study of Chios Mastic Water in Dyspepsia
Led by Harokopio University · Updated on 2025-09-15
60
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chios mastic is a natural product with strong antimicrobial, anti-inflammatory and antioxidant properties, and well-established benefits for dyspeptic disorders. The aim of the present study is to investigate the effectiveness of a natural aqueous extract of Chios mastic (mastic water), a by-product of Chios mastic processing, in the management of dyspepsia. This will be a 3-month randomized double-blind controlled clinical trial in adults with dyspepsia. Participants will be blindly randomized to an intervention group, which will receive 600 mL/d of a carbonated beverage enriched with Chios mastic water (0.2%), or a control group, which will receive 600 mL/d of an identical placebo beverage with no active ingredients. Participants will be evaluated in terms of anthropometric indices, lifestyle habits, severity of dyspepsia-related gastrointestinal symptoms, quality of life, as well as biochemical markers, both pre- and post-intervention.
CONDITIONS
Official Title
A Study of Chios Mastic Water in Dyspepsia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 30 to 60 years old
- Body mass index between 20 and 35 kg/m2
- Presence of dyspepsia
You will not qualify if you...
- Chronic diseases such as diabetes mellitus, cancer, cardiovascular, hepatic, renal, respiratory, chronic inflammatory, or psychiatric diseases
- Other chronic gastrointestinal diseases including gastroesophageal reflux, inflammatory bowel disease, and celiac disease
- Use of immunosuppressants, anti-inflammatories, antibiotics, or corticosteroids
- Use of dietary supplements or products containing Chios mastic
- Excessive alcohol consumption (more than 210 g/week for men and 140 g/week for women)
- Currently on a weight-loss diet or recent significant lifestyle changes within 6 months
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University of Athens
Kallithea, Attica, Greece, 17676
Actively Recruiting
Research Team
G
Giannis Arnaoutis, PhD
CONTACT
M
Michael Georgoulis, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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