Study of Chios Mastic Water Drink for Adults With Dyspepsia 3-Month Randomized, Double-Blind Trial Comparing Mastic Water Beverage to Placebo

What this Trial Is About

Dyspepsia includes a variety of upper digestive symptoms such as abdominal pain, bloating, nausea, and heartburn, affecting up to 40% of people worldwide and lowering quality of life. This study evaluates a natural product called Chios mastic water, which has antimicrobial, anti-inflammatory, and antioxidant properties. Researchers aim to see if a beverage enriched with this extract can improve dyspepsia symptoms and quality of life in adults. This is a 3-month randomized, double-blind controlled clinical trial involving adults aged 30 to 60 years with dyspepsia. Participants are randomly assigned to one of two groups the intervention group receives 600 mL daily of a sparkling beverage enriched with 0.2% natural mastic aqueous extract, while the control group receives an identical placebo beverage without active ingredients. Both groups consume three 200 mL bottles daily for three months. Participants are asked to maintain their usual diet, physical activity, and medical treatments during the trial. The study team and participants are blinded to group assignments. At the start and end of the study, researchers assess body measurements, lifestyle habits, dyspepsia symptom severity, and quality of life. Blood samples are collected to measure biochemical markers like glucose metabolism, liver enzymes, and inflammatory markers. Researchers monitor side effects and may stop the intervention if needed. The primary outcome is the change in dyspepsia symptom severity after 12 weeks, along with changes in quality of life and inflammatory markers.

A Study of Chios Mastic Water in Dyspepsia