Actively Recruiting

Age: 18Years +
All Genders
NCT06477783

Study on the Clinical Efficacy of Teclistamab

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2025-03-12

100

Participants Needed

17

Research Sites

143 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

J

Janssen Pharmaceutica

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this study is to assess the clinical efficacy and safety of the anti-BCMA/CD3 bispecific antibody teclistamab (Tecvayli®) in a prospective, real-life setting in Belgium.

CONDITIONS

Official Title

Study on the Clinical Efficacy of Teclistamab

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Written informed consent
  • Diagnosis of relapsed and refractory multiple myeloma
  • Received at least three previous treatments
  • Refractory to at least one proteasome inhibitor, one immunomodulatory agent, and an anti-CD38 monoclonal antibody
  • Evidence of disease progression on the last line of therapy based on IMWG response criteria
  • Starting teclistamab treatment per routine care or started within 14 days before screening
Not Eligible

You will not qualify if you...

  • Participation in a teclistamab trial or teclistamab Single Patient Request program
  • Started teclistamab treatment more than 14 days before screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 17 locations

1

Imelda

Bonheiden, Antwerpen, Belgium, 2820

Not Yet Recruiting

2

Universitair Ziekenhuis Antwerpen (UZA)

Edegem, Antwerpen, Belgium, 2500

Actively Recruiting

3

Grand Hôpital de Charleroi

Charleroi, Henegouwen, Belgium, 6000

Actively Recruiting

4

EpiCURA

Hornu, Henegouwen, Belgium, 7301

Actively Recruiting

5

CHU Ambroise Paré

Mons, Henegouwen, Belgium, 7000

Actively Recruiting

6

Jessa Ziekenhuis

Hasselt, Limburg, Belgium, 3500

Actively Recruiting

7

CHR Citadelle

Liège, Liège, Belgium, 4000

Actively Recruiting

8

CHU Liège

Liège, Liège, Belgium, 4000

Actively Recruiting

9

CHU UCL Namur

Yvoir, Namur, Belgium, 5530

Actively Recruiting

10

Algemeen Ziekenhuis Maria Middelares (AZMM)

Ghent, Oost-Vlaanderen, Belgium, 9000

Actively Recruiting

11

Universitair Ziekenhuis Gent (UZ Gent)

Ghent, Oost-Vlaanderen, Belgium, 9000

Actively Recruiting

12

Vitaz

Sint-Niklaas, Oost-Vlaanderen, Belgium, 9100

Actively Recruiting

13

Institut Jules Bordet

Brussels, Vlaams-Brabant, Belgium, 1070

Actively Recruiting

14

UCL Saint Luc

Brussels, Vlaams-Brabant, Belgium, 1200

Actively Recruiting

15

AZ Groeninge

Kortrijk, West-Vlaanderen, Belgium, 8500

Actively Recruiting

16

AZ Delta

Roeselare, West-Vlaanderen, Belgium, 8800

Actively Recruiting

17

UZ Leuven Gasthuisberg

Leuven, Belgium, 3000

Actively Recruiting

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Research Team

M

Michel Delforge, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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