Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT07175493

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Led by Keymed Biosciences Co.Ltd · Updated on 2025-12-17

158

Participants Needed

3

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the efficacy and safety of CM336 (BCMA/CD3 Bispecific Antibody) in the treatment of patients with relapsed or refractory autoimmune cytopenia

CONDITIONS

Official Title

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntary provision of written informed consent and ability to comply with protocol requirements.
  • Age 18 years or older, male or female.
  • Eastern Cooperative Oncology Group Performance Status of 0 to 2.
  • Confirmed diagnosis of immune thrombocytopenia, warm autoimmune hemolytic anemia, cold agglutinin disease, mixed autoimmune hemolytic anemia, or Evans Syndrome.
  • Relapsed or refractory autoimmune hemolytic anemia.
Not Eligible

You will not qualify if you...

  • Secondary immune thrombocytopenia or autoimmune hemolytic anemia caused by any reason.
  • Other types of autoimmune hemolytic anemia or other types of cytopenia.
  • History of critical diseases that pose a safety risk or could affect study results.
  • Previous treatment with anti-B Cell Maturation Antigen antibody.
  • Investigator's judgment of unsuitability for participation.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Henan Cancer Hospital

Zhengzhou, Henan, China

Actively Recruiting

2

Heping Hospital Affiliated to Changzhi Medical College

Changzhi, Shanxi, China

Actively Recruiting

3

Blood Disease Hospital, Chinese Academy of Medical Sciences

Tianjin, Tianjin Municipality, China

Actively Recruiting

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Research Team

Q

Qian Jia

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

1

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